Articles with "idh1 fine" as a keyword



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IDH1 fine-tunes cap-dependent translation initiation

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Published in 2019 at "Journal of Molecular Cell Biology"

DOI: 10.1093/jmcb/mjz082

Abstract: Abstract The metabolic enzyme isocitrate dehydrogenase 1 (IDH1) catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG). Its mutation often leads to aberrant gene expression in cancer. IDH1 was reported to bind thousands of RNA… read more here.

Keywords: dependent translation; translation initiation; idh1 fine; idh1 ... See more keywords