Pathophysiology of idiopathic gastroparesis and implications for therapy
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DOI: 10.1080/00365521.2018.1558280
Abstract: Abstract Objectives: Idiopathic gastroparesis is a gastric motility disorder characterized by chronic upper gastrointestinal symptoms and delayed gastric emptying without an identifiable underlying condition. This review summarizes recent understanding of the pathophysiology and treatment of… read more here.
Keywords: pathophysiology idiopathic; treatment; gastroparesis; gastroparesis implications ... See more keywords
P378 A novel approach to managing patients with idiopathic gastroparesis
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DOI: 10.1136/gutjnl-2020-bsgcampus.452
Abstract: Introduction Patients with idiopathic gastroparesis often have difficult to manage upper gastrointestinal symptoms, resulting in many requiring enteral nutrition and becoming high service users. It is known that many of these patients will have previously… read more here.
Keywords: patients idiopathic; gastroenterology; approach; idiopathic gastroparesis ... See more keywords
Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis
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DOI: 10.1186/s12920-018-0379-1
Abstract: BackgroundCellular changes described in human gastroparesis have revealed a role for immune dysregulation, however, a mechanistic understanding of human gastroparesis and the signaling pathways involved are still unclear.MethodsDiabetic gastroparetics, diabetic non-gastroparetic controls, idiopathic gastroparetics and… read more here.
Keywords: diabetic idiopathic; diabetic gastroparesis; gastroparesis; immune dysregulation ... See more keywords
Enrichment of Patients With Ehlers Danlos Syndrome in Idiopathic Gastroparesis—A Gene Set Enrichment Analysis
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DOI: 10.14309/ctg.0000000000000521
Abstract: INTRODUCTION: Ehlers Danlos syndrome (EDS) is a heritable disorder of the connective tissue usually inherited as an autosomal dominant trait. We observe an enrichment of EDS cases in a gastroparesis clinical study. METHODS: We explored… read more here.
Keywords: gastroparesis; danlos syndrome; enrichment; analysis ... See more keywords