Medications for daytime sleepiness in individuals with idiopathic hypersomnia
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DOI: 10.1002/14651858.cd012714
Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of medications for daytime sleepiness and related symptoms in individuals with idiopathic hypersomnia, and in particular whether… read more here.
Keywords: sleepiness individuals; individuals idiopathic; idiopathic hypersomnia; daytime sleepiness ... See more keywords
Comparative polysomnography parameters between narcolepsy type 1/type 2 and idiopathic hypersomnia: A systematic review and meta-analysis.
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DOI: 10.1016/j.smrv.2022.101610
Abstract: A meta-analysis exploring polysomnography (PSG) differences between narcolepsy type 1 (NT1)/type 2 (NT2) and idiopathic hypersomnia (IH), particularly one that stratifies the analysis by IH with and without long sleep time (LST), could provide information… read more here.
Keywords: analysis; narcolepsy type; idiopathic hypersomnia; polysomnography ... See more keywords
Update on treatment for idiopathic hypersomnia
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DOI: 10.1080/13543784.2018.1417385
Abstract: ABSTRACT Introduction: Idiopathic hypersomnia (IH) is a poorly characterized orphan central disorder of hypersomnolence responsible for excessive daytime sleepiness (EDS), prolonged nighttime sleep and sleep inertia that often require long-term symptomatic stimulant medication. To date,… read more here.
Keywords: treatment; treatment idiopathic; idiopathic hypersomnia; update treatment ... See more keywords
0748 A Novel, Non-Pharmacological Treatment Option for Patients With Idiopathic Hypersomnia
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DOI: 10.1093/sleep/zsaa056.744
Abstract: There is some evidence suggesting that patients with hypersomnia have delayed circadian timing, which could explain, at least in part, the excessive sleepiness and impaired daytime performance experienced by these individuals. This study investigated the… read more here.
Keywords: baseline treatment; treatment; idiopathic hypersomnia; pharmacological treatment ... See more keywords
494 Placebo-Controlled, Double-Blind, Randomized Withdrawal Study of Lower-Sodium Oxybate in Adults With Idiopathic Hypersomnia
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DOI: 10.1093/sleep/zsab072.493
Abstract: Idiopathic hypersomnia (IH) is a rare central hypersomnolence disorder characterized by excessive daytime sleepiness, prolonged nighttime sleep, and sleep inertia. No US/EU medication is approved for treatment of IH. Lower-sodium oxybate (LXB; Xywav™; previously designated… read more here.
Keywords: lxb; sodium oxybate; idiopathic hypersomnia; placebo ... See more keywords
499 Utilization of Diagnostic Sleep Testing Prior to Idiopathic Hypersomnia Diagnosis Among US Adults: A Real-World Claims Analysis
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DOI: 10.1093/sleep/zsab072.498
Abstract: A retrospective analysis was conducted to characterize diagnostic sleep testing during the 12 months before diagnosis of idiopathic hypersomnia (IH), a hypersomnolence disorder with no approved treatments. IBM® MarketScan® claims data were analyzed (1/1/14–9/30/19) to… read more here.
Keywords: diagnosis; sleep testing; diagnostic sleep; overall primary ... See more keywords
0592 Efficacy of Lower-Sodium Oxybate by Baseline Sleep Inertia in a Phase 3 Clinical Study in Patients With Idiopathic Hypersomnia
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DOI: 10.1093/sleep/zsad077.0592
Abstract: Idiopathic hypersomnia is a debilitating neurologic sleep disorder. Sleep inertia (difficulty awakening) is a common symptom that can significantly impair functioning and quality of life. This post hoc analysis evaluated response to lower-sodium oxybate (LXB;… read more here.
Keywords: baseline sleep; idiopathic hypersomnia; sleep inertia; inertia ... See more keywords
0838 Diagnosed Prevalence of Idiopathic Hypersomnia Among Adults in the United States
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DOI: 10.1093/sleep/zsad077.0838
Abstract: Idiopathic hypersomnia (IH) is a rare neurologic disorder that can cause debilitating symptoms, including excessive daytime sleepiness, severe sleep inertia, prolonged nighttime sleep, long and unrefreshing naps, and cognitive dysfunction. Research reporting the burden of… read more here.
Keywords: idiopathic hypersomnia; among adults; prevalence; 2019 2020 ... See more keywords
0847 Real-World Idiopathic Hypersomnia Total Health Model (RHYTHM): Clinical Burden of Patients Diagnosed With Idiopathic Hypersomnia
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DOI: 10.1093/sleep/zsad077.0847
Abstract: Idiopathic hypersomnia (IH) is a rare neurologic disorder that can cause debilitating symptoms, including excessive daytime sleepiness, severe sleep inertia, prolonged nighttime sleep, long and unrefreshing naps, and cognitive dysfunction. Limited research has investigated the… read more here.
Keywords: idiopathic hypersomnia; clinical burden; patients diagnosed; non controls ... See more keywords
Pupillometry to differentiate idiopathic hypersomnia from narcolepsy type 1.
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DOI: 10.1111/jsr.13885
Abstract: Idiopathic hypersomnia is poorly diagnosed in the absence of biomarkers to distinguish it from other central hypersomnia subtypes. Given that light plays a main role in the regulation of sleep and wake, we explored the… read more here.
Keywords: hypersomnia; idiopathic hypersomnia; hypersomnia narcolepsy; narcolepsy type ... See more keywords
Development and Validation of the Pediatric Hypersomnolence Survey
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DOI: 10.1212/wnl.0000000000200187
Abstract: Background and Objectives Narcolepsy and idiopathic hypersomnia usually begin in early adolescence, but diagnostic delays ranging from 5 to 10 years are common, affecting disease burden. To improve early identification of these treatable conditions, we… read more here.
Keywords: survey; idiopathic hypersomnia; hypersomnolence survey; pediatric hypersomnolence ... See more keywords