Does Zika virus infection induce prolonged remissions in children with idiopathic nephrotic syndrome?
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3588-5
Abstract: BackgroundZika is an emerging mosquito-borne flavivirus. We report two pediatric patients diagnosed with idiopathic nephrotic syndrome who achieved complete remission of the disease after suffering Zika virus (ZIKV) infection.Case Diagnosis/TreatmentThe first patient was a young… read more here.
Keywords: idiopathic nephrotic; zikv infection; infection; zika virus ... See more keywords
Uteroglobin gene polymorphism (G38A) may be a risk factor in childhood idiopathic nephrotic syndrome
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DOI: 10.1007/s00467-017-3800-7
Abstract: BackgroundUteroglobin (UG) is a multifunctional protein with anti-inflammatory properties. The aim of this study was to first evaluate the role of UG gene G38A polymorphism in childhood idiopathic nephrotic syndrome (INS), and determine whether this… read more here.
Keywords: childhood idiopathic; nephrology; idiopathic nephrotic; gene ... See more keywords
FCGR2A single nucleotide polymorphism confers susceptibility to childhood-onset idiopathic nephrotic syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "Immunology letters"
DOI: 10.1016/j.imlet.2017.11.002
Abstract: Childhood-onset idiopathic nephrotic syndrome affects 1.15-3.4 children/100,000 children/year in Western Countries. Immune-mediated mechanisms, particularly T cell-mediated, are thought to play a key pathogenic role. The genetic basis of the disease is still poorly understood. We… read more here.
Keywords: fcgr2a; idiopathic nephrotic; association; childhood onset ... See more keywords
Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2017.12.001
Abstract: BACKGROUND Idiopathic nephrotic syndrome (INS) is one of the most common renal diseases in the pediatric population; considering the role of the immune system in its pathogenesis, corticosteroids are used as first-line immunosuppressive treatment. Due… read more here.
Keywords: idiopathic nephrotic; mesenchymal stromal; functional characterization; stromal cells ... See more keywords
Bone densitometry in children with idiopathic nephrotic syndrome on prolonged steroid therapy: A tertiary multicenter study
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DOI: 10.1097/md.0000000000029860
Abstract: Long-term glucocorticoids administration inhibits bone mineralization and has a negative impact on basic cellular mechanisms that are critical in the development and maintenance of bone strength. Steroids can cause osteoporosis in children and have a… read more here.
Keywords: bmd; idiopathic nephrotic; bone; therapy ... See more keywords
Hypomethylation of NLRP3 gene promoter discriminates glucocorticoid‐resistant from glucocorticoid‐sensitive idiopathic nephrotic syndrome patients
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Translational Science"
DOI: 10.1111/cts.12961
Abstract: To assess whether NLRP3 gene promoter methylation was able to discriminate glucocorticoid (GC)‐resistant from GC‐sensitive idiopathic nephrotic syndrome (INS), patients with minimal change disease (MCD) or focal segmental glomerulosclerosis (FSGS), we measured the methylation level… read more here.
Keywords: gene promoter; idiopathic nephrotic; sensitive idiopathic; promoter ... See more keywords
Gut Microbiota Profile in Adult Patients with Idiopathic Nephrotic Syndrome
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DOI: 10.1155/2021/8854969
Abstract: Background Increasing evidences have reported gut microbiota dysbiosis in many diseases, including chronic kidney disease and pediatric idiopathic nephrotic syndrome (INS). There is lack evidence of intestinal microbiota dysbiosis in adults with INS, however. Here,… read more here.
Keywords: idiopathic nephrotic; microbiota; gut microbiota; adult patients ... See more keywords
Idiopathic nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Internal Medicine"
DOI: 10.32388/8wu7ic
Abstract: Abstract We used decision analysis to compare the conventional strategy of biopsy-tailored therapy with alternative strategies not using renal biopsy in treating adults with idiopathic nephrotic sy... read more here.
Keywords: medicine; idiopathic nephrotic; nephrotic syndrome;
Altered B-Lymphocyte Homeostasis in Idiopathic Nephrotic Syndrome
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DOI: 10.3389/fped.2019.00377
Abstract: Background: B-cell-deleted therapy has been successfully used for children with idiopathic nephrotic syndrome (INS), suggesting that B cells may be involved in the pathogenesis of INS. B cells are a heterogenous population comprised of subpopulations… read more here.
Keywords: homeostasis; idiopathic nephrotic; nephrotic syndrome; cell ... See more keywords
Assessment of Brain-Derived Neurotrophic Factor (BDNF) Concentration in Children with Idiopathic Nephrotic Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012312
Abstract: Idiopathic nephrotic syndrome (INS) is a chronic disease affecting children in early childhood. It is characterized by proteinuria, hypoalbuminemia, edema and hyperlipidemia. To date, the diagnosis is usually established at an advanced stage of proteinuria.… read more here.
Keywords: idiopathic nephrotic; concentration; bdnf; nephrotic syndrome ... See more keywords
Assessment of Interleukin-15 (IL-15) Concentration in Children with Idiopathic Nephrotic Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24086993
Abstract: Idiopathic nephrotic syndrome (INS) is a chronic glomerular disease in children, characterized by severe proteinuria, hypoalbuminemia, and/or presence of edema and hyperlipidemia. The pathogenesis, however, has not been yet established. The clinical course of the… read more here.
Keywords: idiopathic nephrotic; disease; concentration; nephrotic syndrome ... See more keywords