Differences in efficacy and safety of lubiprostone used for idiopathic vs opioid-induced constipation: meta-analysis of East Asian and Western populations.
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DOI: 10.3164/jcbn.19-118
Abstract: Several secretagogues, such as lubiprostone, have been developed for the treatment of constipation in the last 10 years. It is unclear whether the efficacy of lubiprostone for spontaneous bowel movement (SBM) and the adverse events… read more here.
Keywords: idiopathic opioid; induced constipation; western populations; opioid induced ... See more keywords