Screening of Inhibitors Targeting Heat Shock Protein 47 Involved in the Development of Idiopathic Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2021 at "ChemMedChem"
DOI: 10.1002/cmdc.202100064
Abstract: Heat shock protein 47 (HSP47), a collagen‐specific molecular chaperone, is causally related to fibrotic diseases, including idiopathic pulmonary fibrosis. The identification of Compounds that interfere with the HSP47‐collagen interaction is essential for the development of… read more here.
Keywords: protein; idiopathic pulmonary; heat shock; pulmonary fibrosis ... See more keywords
Circulating plasmablasts are elevated and produce pathogenic anti‐endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747460
Abstract: Idiopathic pulmonary arterial hypertension (IPAH) is a devastating pulmonary vascular disease in which autoimmune and inflammatory phenomena are implicated. B cells and autoantibodies have been associated with IPAH and identified as potential therapeutic targets. However,… read more here.
Keywords: idiopathic pulmonary; arterial hypertension; endothelial cell; pulmonary arterial ... See more keywords
Targeting anti‐aging protein sirtuin (Sirt) in the diagnosis of idiopathic pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28033
Abstract: Idiopathic pulmonary fibrosis (IPF) is a severe, incurable, age‐associated respiratory disorder that has gained significance because of its unknown etiology and lack of therapeutic approaches. IPF causes maximum damage to the alveolar epithelial cells, thereby… read more here.
Keywords: protein; fibrosis; diagnosis; idiopathic pulmonary ... See more keywords
A nonsynonymous polymorphism (rs117179004, T392M) of hyaluronidase 1 (HYAL1) is associated with increased risk of idiopathic pulmonary fibrosis in Southern Han Chinese
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23782
Abstract: Idiopathic pulmonary fibrosis (IPF) is a genetic heterogeneous disease with high mortality and poor prognosis. Hyaluronidase 1 (HYAL1) was found to be upregulated in fibroblasts from IPF patients, and overexpression of HYAL1 could prevent human… read more here.
Keywords: idiopathic pulmonary; hyaluronidase hyal1; pulmonary fibrosis; hyal1 ... See more keywords
Detection of interstitial pneumonia with autoimmune features and idiopathic pulmonary fibrosis are enhanced by involvement of matrix metalloproteinases levels and clinical diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24734
Abstract: Higher detection of interstitial pneumonia with autoimmune features (IPAF), and idiopathic pulmonary fibrosis (IPF), has significant diagnostic and therapeutic implications. Some matrix metalloproteinases (MMPs) have become reliable diagnostic biomarkers in IPAF and IPF in previous… read more here.
Keywords: detection interstitial; autoimmune features; idiopathic pulmonary; pulmonary fibrosis ... See more keywords
Development and applicability of a dignity‐centred palliative care programme for people with idiopathic pulmonary fibrosis: A qualitative‐driven mixed methods study
Sign Up to like & getrecommendations! Published in 2022 at "Nursing Open"
DOI: 10.1002/nop2.1274
Abstract: This study evaluated the acceptability of a dignity‐centred palliative care programme for people with idiopathic pulmonary fibrosis by converging perceptions of living with idiopathic pulmonary fibrosis qualitative data and quantitative data. read more here.
Keywords: centred palliative; idiopathic pulmonary; palliative care; pulmonary fibrosis ... See more keywords
Updates in idiopathic pulmonary hemosiderosis in 2022: A state of the art review
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.26230
Abstract: This manuscript reports the recent advances in idiopathic pulmonary hemosiderosis (IPH), a rare cause of diffuse alveolar hemorrhage in children and adults. This narrative review of the literature summarizes different aspects of IPH, including proposed… read more here.
Keywords: pulmonary hemosiderosis; idiopathic pulmonary; review; disease ... See more keywords
The impact of cardiovascular comorbidities associated with risk for left heart disease on idiopathic pulmonary arterial hypertension: Data from the Hellenic Pulmonary Hypertension Registry (HOPE)
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12086
Abstract: Abstract Whereas younger female patients were diagnosed with idiopathic pulmonary arterial hypertension (IPAH) in 1980s, it is now frequently encountered in elderly patients with cardiovascular comorbidities (CVCs) associated with increased risk for left heart disease.… read more here.
Keywords: arterial hypertension; idiopathic pulmonary; hypertension; disease ... See more keywords
Utilizing a Homecare Platform for Remote Monitoring of Patients with Idiopathic Pulmonary Fibrosis.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-57348-9_15
Abstract: Homecare and home telemonitoring are a focal point of emerging healthcare schemes, with proven benefits for both patients, caregivers and providers, including reduction of healthcare costs and improved patients' quality of life, especially in the… read more here.
Keywords: idiopathic pulmonary; monitoring; pulmonary fibrosis; monitoring patients ... See more keywords
Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-020-03693-7
Abstract: Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an abnormal fibrotic response involving vast areas of the lungs. Given the poor… read more here.
Keywords: molecular determinants; idiopathic pulmonary; emerging cellular; pulmonary fibrosis ... See more keywords
Outcomes of idiopathic pulmonary arterial hypertension in Japanese children: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2021 at "Heart and Vessels"
DOI: 10.1007/s00380-021-01806-1
Abstract: Recently, targeted therapy has been developed for idiopathic pulmonary arterial hypertension (IPAH). Studies evaluating the prognosis of IPAH have been conducted in adults. However, there is no nationwide survey of pediatric patients with IPAH regarding… read more here.
Keywords: idiopathic pulmonary; retrospective cohort; arterial hypertension; japanese children ... See more keywords