Intrinsically Disordered Proteins Link Alternative Splicing and Post-Translational Modifications to Complex Cell Signaling and Reulation
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2017.11.479
Abstract: Intrinsically disordered proteins and regions (IDPs and IDRs) lack well-defined tertiary structures, yet carry out various important cellular functions, especially those associated with cell signaling and regulation. In eukaryotes, IDPs and IDRs contain the preferred… read more here.
Keywords: idps idrs; cell signaling; cell; alternative splicing ... See more keywords
Intrinsically Disordered Proteins Link Alternative Splicing and Post-translational Modifications to Complex Cell Signaling and Regulation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.03.028
Abstract: Intrinsically disordered proteins and regions (IDPs and IDRs) lack well-defined tertiary structures, yet carry out various important cellular functions, especially those associated with cell signaling and regulation. In eukaryotes, IDPs and IDRs contain the preferred… read more here.
Keywords: idps idrs; cell signaling; signaling regulation; cell ... See more keywords
Characterization of intrinsically disordered regions in proteins informed by human genetic diversity
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1009911
Abstract: All proteomes contain both proteins and polypeptide segments that don’t form a defined three-dimensional structure yet are biologically active—called intrinsically disordered proteins and regions (IDPs and IDRs). Most of these IDPs/IDRs lack useful functional annotation… read more here.
Keywords: intrinsically disordered; characterization intrinsically; disordered regions; regions proteins ... See more keywords
Genomic Analysis of Intrinsically Disordered Proteins in the Genus Camelus
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21114010
Abstract: Intrinsically disordered proteins/regions (IDPs/IDRs) fail to fold completely into 3D structures, but have major roles in determining protein function. While natively disordered proteins/regions have been found to fulfill a wide variety of primary cellular roles,… read more here.
Keywords: idps idrs; analysis; genus camelus; proteins regions ... See more keywords