Feasibility and performance of the Idylla™ NRAS/BRAF cartridge mutation assay on thyroid liquid-based fine-needle aspiration.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic cytopathology"
DOI: 10.1002/dc.24897
Abstract: BACKGROUND Thyroid nodules with indeterminate cytology represent up to 30% of cases. Molecular testing is now highly recommended to improve management. This study aimed to evaluate the use of the Idylla™ NRAS/BRAF mutation test, a… read more here.
Keywords: mutation; idylla nras; braf; idylla ... See more keywords
KRAS and NRAS mutational analysis in plasma ctDNA from patients with metastatic colorectal cancer by real-time PCR and digital PCR
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-022-04126-6
Abstract: Mutations in the KRAS and NRAS (RAS) genes are negative predictors of response to anti-EGFR therapy in metastatic colorectal cancer (mCRC). The detection of mutations in circulating tumor DNA (ctDNA) has emerged as a less… read more here.
Keywords: analysis; metastatic colorectal; kras nras; ctdna ... See more keywords
Detection of microsatellite instability with Idylla MSI assay in colorectal and endometrial cancer
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03082-w
Abstract: Universal testing of microsatellite instability (MSI) is recommended for colorectal cancer (CRC) and endometrial cancer (EC) to screen for Lynch syndrome and to aid in assessing prognosis and optimal treatment. We compared the performance of… read more here.
Keywords: test; idylla; endometrial cancer; microsatellite instability ... See more keywords
Rapid BRAF mutation tests in patients with advanced melanoma: comparison of immunohistochemistry, Droplet Digital PCR, and the Idylla Mutation Platform
Sign Up to like & getrecommendations! Published in 2018 at "Melanoma Research"
DOI: 10.1097/cmr.0000000000000421
Abstract: BRAF mutational testing has become a common practice in the diagnostic process of patients with advanced melanoma. Although time-consuming, DNA sequencing techniques are the current gold standard for mutational testing. However, in certain clinical situations,… read more here.
Keywords: mutation; droplet digital; idylla; braf mutation ... See more keywords
Ultra-rapid Idylla™ EGFR mutation screening followed by next-generation sequencing: An integrated solution to molecular diagnosis of non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1064487
Abstract: Background Rapid profiling of the EGFR mutations is crucial to help clinicians choose the optimal treatment for patients with advanced/metastatic Non-Small Cell Lung Cancer (NSCLC). Unfortunately, current diagnostic techniques, including ARMS-PCR and NGS, generally require… read more here.
Keywords: non small; idylla system; idylla; small cell ... See more keywords
Utility of Select Gene Mutation Detection in Tumors by the Idylla Rapid Multiplex PCR Platform in Comparison to Next-Generation Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13050799
Abstract: Testing of tumors by next generation sequencing (NGS) is impacted by relatively long turnaround times and a need for highly trained personnel. Recently, Idylla oncology assays were introduced to test for BRAF, EGFR, KRAS, and… read more here.
Keywords: idylla; kras nras; utility select; next generation ... See more keywords