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   Articles with "iecs" as a keyword



Inhibition of LncRNA-NEAT1 alleviates intestinal epithelial cells (IECs) dysfunction in ulcerative colitis by maintaining the homeostasis of the glucose metabolism through the miR-410-3p-LDHA axis

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2037957

Abstract: ABSTRACT Dysfunction of intestinal epithelial cells (IECs) leads to intestinal epithelial barrier damage and critically involves in the pathogenesis and development of ulcerative colitis (UC). Accumulating studies revealed essential functions of non-coding RNAs in UC.… read more here.

Keywords: glucose metabolism; dysfunction; mir 410; iecs ... See more keywords

A Novel RIPK1 Inhibitor Reduces GVHD in Mice via a Non-immunosuppressive Mechanism that Restores Intestinal Homeostasis.

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recommendations! Published in 2022 at "Blood"

DOI: 10.1182/blood.2022017262

Abstract: Intestinal epithelial cells (IECs) are implicated in the propagation of T cell-mediated inflammatory diseases including graft-versus-host disease (GVHD), but the underlying mechanism remains poorly defined. Here, we report that IECs require receptor-interacting protein kinase-3 (RIPK3)… read more here.

Keywords: cell; ripk3; ripk1; mechanism ... See more keywords

Primary cultures of mouse small intestinal epithelial cells using the dissociating enzyme type I collagenase and hyaluronidase

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recommendations! Published in 2017 at "Brazilian Journal of Medical and Biological Research"

DOI: 10.1590/1414-431x20175831

Abstract: The epithelium is a highly dynamic system, which plays a crucial role in the homeostasis of the intestinal tract. However, studies on the physiological and pathophysiological functions of intestinal epithelial cells (IECs) have been hampered… read more here.

Keywords: epithelial cells; intestinal epithelial; small intestinal; type collagenase ... See more keywords

Enterovirus 71 Antagonizes Antiviral Effects of Type III Interferon and Evades the Clearance of Intestinal Intraepithelial Lymphocytes

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recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2021.806084

Abstract: Enterovirus 71 (EV71) is the major pathogen causing severe neurological complications and hand, foot, and mouth disease. The intestinal mucosal immune system has a complete immune response and immune regulation mechanism, consisting of densely arranged… read more here.

Keywords: type iii; infection; intestinal mucosal; intestinal intraepithelial ... See more keywords