A novel MBTPS2 start codon mutation causes a mild ichthyosis follicularis with atrichia and photophobia phenotype
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.14114
Abstract: Ichthyosis follicularis with atrichia and photophobia (IFAP; MIM 308205) syndrome is a rare, X-linked, oculocutaneous human disorder, which is caused by mutations in the gene MBTPS2. We report a Chinese family with one affected child,… read more here.
Keywords: phenotype; dermatology; start codon; ifap ... See more keywords
Design, Synthesis and Preclinical Assessment of 99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27010264
Abstract: Fibroblast activation protein (FAP) is expressed in the microenvironment of most human epithelial tumors. 68Ga-labeled FAP inhibitors based on the cyanopyrrolidine structure (FAPI) are currently used for the detection of the tumor microenvironment by PET… read more here.
Keywords: activation protein; fibroblast activation; ifap; protein fap ... See more keywords
Targeted Endoradiotherapy with Lu2O3-iPSMA/-iFAP Nanoparticles Activated by Neutron Irradiation: Preclinical Evaluation and First Patient Image
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14040720
Abstract: Prostate-specific membrane antigen (PSMA) is expressed in a variety of cancer cells, while the fibroblast activation protein (FAP) is expressed in the microenvironment of tumors. Previously, we reported the ability of iPSMA and iFAP ligands… read more here.
Keywords: 177lu2o3 ifap; 177lu2o3 ipsma; ipsma; ifap ... See more keywords