Interferon Inducer IFI35 Regulates RIG-I-Mediated Innate Antiviral Response through Mutual Antagonism with Influenza Virus Protein NS1
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DOI: 10.1128/jvi.00283-21
Abstract: Influenza A virus (IAV) infection poses a global health threat and is among the most common contagious pathogens to cause severe respiratory infections in humans and animals. ISGs play a key role in host defense… read more here.
Keywords: ifi35; interferon; infection; virus ... See more keywords
IFI35 is involved in the regulation of the radiosensitivity of colorectal cancer cells
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DOI: 10.1186/s12935-021-01997-7
Abstract: Background Interferon regulatory factor-1 (IRF1) affects the proliferation of colorectal cancer (CRC). Recombinant interferon inducible protein 35 (IFI35) participates in immune regulation and cell proliferation. The aim of the study was to examine whether IRF1… read more here.
Keywords: colorectal cancer; ifi35; crc; irf1 ... See more keywords
IFI35 Promotes Renal Cancer Progression by Inhibiting pSTAT1/pSTAT6-Dependent Autophagy
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DOI: 10.3390/cancers14122861
Abstract: Simple Summary Interferon-induced protein 35 (IFI35) plays an important role in virus-related immune inflammatory responses. However, the biological significance and function of IFI35 in cancer is still not well understood. Our goal is to explore… read more here.
Keywords: renal cancer; rcc; ifi35; pstat1 pstat6 ... See more keywords