Cap-related modifications of RNA regulate binding to IFIT proteins
Sign Up to like & getrecommendations! Published in 2024 at "RNA"
DOI: 10.1261/rna.080011.124
Abstract: All cells in our body are equipped with receptors to recognize pathogens and trigger a rapid defense response. As a result, foreign molecules are blocked and cells are alerted to the danger. Among the many… read more here.
Keywords: cap related; ifit; binding; ifit proteins ... See more keywords
Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection
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DOI: 10.1371/journal.ppat.1007674
Abstract: Viral myocarditis is a serious disease, commonly caused by type B coxsackieviruses (CVB). Here we show that innate immune protection against CVB3 myocarditis requires the IFIT (IFN-induced with tetratricopeptide) locus, which acts in a biphasic… read more here.
Keywords: infection; ifit; biphasic cardiomyocyte; replication ... See more keywords