Cap-related modifications of RNA regulate binding to IFIT proteins
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DOI: 10.1261/rna.080011.124
Abstract: All cells in our body are equipped with receptors to recognize pathogens and trigger a rapid defense response. As a result, foreign molecules are blocked and cells are alerted to the danger. Among the many… read more here.
Keywords: cap related; ifit; binding; ifit proteins ... See more keywords
Emerging Functions of Human IFIT Proteins in Cancer
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DOI: 10.3389/fmolb.2019.00148
Abstract: Interferon-induced protein with tetratricopeptide repeats (IFIT) genes are prominent interferon-stimulated genes (ISGs). The human IFIT gene family consists of four genes named IFIT1, IFIT2, IFIT3, and IFIT5. The expression of IFIT genes is very low… read more here.
Keywords: tpr motifs; ifit proteins; ifit genes; human ifit ... See more keywords
How Different Pathologies Are Affected by IFIT Expression
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DOI: 10.3390/v15020342
Abstract: The type-I interferon (IFN) system represents the first line of defense against viral pathogens. Recognition of the virus initiates complex signaling pathways that result in the transcriptional induction of IFNs, which are then secreted. Secreted… read more here.
Keywords: sepsis; ifit proteins; expression; ifit expression ... See more keywords