High IFITM3 expression predicts adverse prognosis in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Gene Therapy"
DOI: 10.1038/s41417-019-0093-y
Abstract: Acute myeloid leukemia (AML) is a malignancy caused by the uncontrolled and dysregulated clonal expansion of abnormal myeloid primordial cells. In general, the prognosis of AML remains poor despite new discoveries in its pathogenesis and… read more here.
Keywords: myeloid leukemia; ifitm3 expression; expression; acute myeloid ... See more keywords
Association of IFITM3 with the efficacy of anti-PD1/PD-L1 therapy and regulation of immunosensitivity via MHC-I regulation in SCLC.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.8105
Abstract: 8105 Background: Majority of small cell lung cancer (SCLC) patients exhibit resistance to immune checkpoint inhibitors (ICIs), which is associated with the downregulation of major histocompatibility complex class I (MHC-I) molecules. This study investigates the… read more here.
Keywords: ifitm3 expression; ifitm3; association ifitm3; regulation ... See more keywords
Ethyl Gallate Inhibits Bovine Viral Diarrhea Virus by Promoting IFITM3 Expression, Lysosomal Acidification and Protease Activity
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108637
Abstract: Bovine viral diarrhea virus (BVDV) is a highly contagious viral disease which causes economic losses to the cattle industry. Ethyl gallate (EG) is a phenolic acid derivative which has various potentials to modulate the host… read more here.
Keywords: ifitm3 expression; activity; bovine viral; bvdv infection ... See more keywords