Interferon γ, IL-17, and IL-1β impair sperm motility and viability and induce sperm apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Cytokine"
DOI: 10.1016/j.cyto.2022.155834
Abstract: Urogenital inflammation is a known cause of male infertility. Increased levels of inflammatory cytokines, leukocyte counts and oxidative stress are highly detrimental for sperm quality thus compromising male fertility. Although cytokines affect sperm by recruiting… read more here.
Keywords: sperm motility; viability; apoptosis; ifn 17a ... See more keywords
Toll-Like Receptor 4–Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Inflammatory Development of Polymyositis by Mediating Interferon-γ and Interleukin-17A in Humans and Experimental Autoimmune Myositis Mouse Model
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2017.00132
Abstract: Objective Toll-like receptor 4 (TLR4) is one of the key players in the development of many autoimmune diseases. To determine the possible role of TLR4 in polymyositis (PM) development, we collected muscle samples from PM… read more here.
Keywords: inflammatory development; eam mice; model; development ... See more keywords