Functional characterization of duck TBK1 in IFN‐&bgr; induction
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.09.007
Abstract: HighlightsduTBK1 is ubiquitously expressed in various duck tissues.duTBK1 contributes to the type I IFN induction via the activation of IRF1 and NF‐&kgr;B.The kinase domain and ubiquitin‐like domain of duTBK1 are essential for IFN‐&bgr; induction.Overexpression of… read more here.
Keywords: ifn bgr; bgr induction; dutbk1; tbk1 ... See more keywords
Functional characterization of duck LSm14A in IFN‐&bgr; induction
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.06.014
Abstract: Abstract Human LSm14A is a key component of processing body (P‐body) assembly that mediates interferon‐&bgr; (IFN‐&bgr;) production by sensing viral RNA or DNA. To the best of our knowledge, we are the first to report… read more here.
Keywords: dulsm14a; duck lsm14a; bgr; ifn bgr ... See more keywords
Molecular cloning and functional characterization of duck DDX41
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DOI: 10.1016/j.dci.2018.07.015
Abstract: ABSTRACT DEAD (Asp–Glu–Ala–Asp) box polypeptide 41 (DDX41), a receptor belonging to DExD/H‐box helicase family, acts as an intracellular DNA sensor and induces type I IFN production in mammals and fish. However, the function of avian… read more here.
Keywords: molecular cloning; ifn bgr; duck ddx41; duck ... See more keywords
S95 Role of ifn&bgr; in modulating innate immunity of primary bronchial epithelial cells (PBECs) during respiratory infection
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.101
Abstract: Introduction There is evidence that an impaired innate immunity, caused by a defect in IFN&bgr; expression in response to viral infections could be linked with exacerbations in asthmatic and COPD patients. So far the administration… read more here.
Keywords: hour; innate immunity; infection; ifn bgr ... See more keywords