Autosomal Dominant IFN-γR1 Deficiency Presenting with both Atypical Mycobacteriosis and Tuberculosis in a BCG-Vaccinated South African Patient
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-018-0509-8
Abstract: To the Editor, Mendelian susceptibility to mycobacterial disease (MSMD) refers to a group of primary immunodeficiency disorders (PIDs) that characteristically cause susceptibility to mycobacterial infections by a range of mycobacteria and to systemic nontyphoidal salmonellosis… read more here.
Keywords: ifn deficiency; dominant ifn; autosomal dominant; msmd ... See more keywords
Tissue specific diversification, virulence and immune response to Mycobacterium bovis BCG in a patient with an IFN-γ R1 deficiency
Sign Up to like & getrecommendations! Published in 2020 at "Virulence"
DOI: 10.1080/21505594.2020.1848108
Abstract: ABSTRACT Summary: We characterized Mycobacterium bovis BCG isolates found in lung and brain samples from a previously vaccinated patient with IFNγR1 deficiency. The isolates collected displayed distinct genomic and phenotypic features consistent with host adaptation… read more here.
Keywords: virulence; ifn deficiency; bovis bcg; brain ... See more keywords