A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma
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DOI: 10.1038/s41598-017-10467-y
Abstract: Lambda interferons (IFNLs) have immunomodulatory functions at epithelial barrier surfaces. IFN-λ4, a recent member of this family is expressed only in a subset of the population due to a frameshift-causing DNA polymorphism rs368234815. We examined… read more here.
Keywords: older asthmatic; aeroallergen sensitization; dna polymorphism; ifn generating ... See more keywords