Profiles of pro‐inflammatory cytokines in allogenic stem cell transplantation with post‐transplant cyclophosphamide
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DOI: 10.1016/j.cyto.2017.08.016
Abstract: Abstract Large number of studies was published about predictive value of cytokines for graft‐versus‐host disease (GVHD) after allogeneic stem cell transplantation. Recently, there has been a growing interest in GVHD prophylaxis with post‐transplant cyclophosphamide (PTCy).… read more here.
Keywords: transplant cyclophosphamide; cell transplantation; post transplant; stem cell ... See more keywords
Reduction of respiratory infections in asthma patients supplemented with vitamin D is related to increased serum IL‐10 and IFN&ggr; levels and cathelicidin expression
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DOI: 10.1016/j.cyto.2018.01.001
Abstract: Background Vitamin D is a molecule that modulates the immune response and shows anti‐inflammatory effects that are beneficial for the control of chronic diseases such as asthma. The trial aim was to explore the effect… read more here.
Keywords: respiratory infections; ifn ggr; asthma patients; supplementation ... See more keywords
IFN&ggr; enhances cytotoxic efficiency of the cytotoxic T lymphocytes against human glioma cells
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.04.003
Abstract: Abstract Cytotoxic T lymphocytes (CTLs) are a key player in cancer immunotherapies, and MHC class I molecules on the cell surface are crucial for cellular recognition. However, the aberrant expression of MHC class I molecules… read more here.
Keywords: glioma; class molecules; glioma cells; ifn ggr ... See more keywords
The positive effects of secreting cytokines IL‐17 and IFN‐&ggr; on the early‐stage differentiation and negative effects on the calcification of primary osteoblasts in vitro
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DOI: 10.1016/j.intimp.2018.02.002
Abstract: Objective: Interleukin‐17 (IL‐17) and interferon‐gamma (IFN‐&ggr;) are all pro‐inflammatory cytokines produced by specific subsets of T‐cells and are also considered crucial regulators in bone remodeling, but their effects on osteogenesis have not been carefully studied.… read more here.
Keywords: positive effects; differentiation; primary osteoblasts; early stage ... See more keywords
Systemic delivery of mesenchymal stem cells condition media in repeated doses acts as magic bullets in restoring IFN‐&ggr;/IL‐4 balance in asthmatic rats
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DOI: 10.1016/j.lfs.2018.09.049
Abstract: Aims: With respect to recent advantage in stem cell application, given the concern reported previously after stem cell transplantation, mesenchymal stem cell‐derived conditioned media (MSC‐CM) could be a potential approach to guarantee more safety and… read more here.
Keywords: sensitized rats; stem cell; ova sensitized; stem ... See more keywords
Vaccination with a CD4+ and CD8+ T‐cell epitopes‐based recombinant chimeric protein derived from Leishmania infantum proteins confers protective immunity against visceral leishmaniasis
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DOI: 10.1016/j.trsl.2018.05.001
Abstract: &NA; Vaccination seems to be the best approach to control visceral leishmaniasis (VL). Resistance against infection is based on the development of a Th1 immune response characterized by the production of interferons‐&ggr; (IFN‐&ggr;), interleukin‐12 (IL‐12),… read more here.
Keywords: cell epitopes; recombinant chimeric; visceral leishmaniasis; based recombinant ... See more keywords
IL‐10 in vitro could enhance IFN&ggr; expression and suppress PD‐1 expression in CD8 T cells from esophageal cancer patients
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DOI: 10.1016/j.yexcr.2019.03.038
Abstract: &NA; IL‐10 is commonly regarded as an immunoregulatory cytokine, but accumulating evidence suggests that IL‐10 may promote CD8 T cell expansion and proliferation. In this study, tumor infiltrating (TI) and peripheral blood (PB) CD8 T… read more here.
Keywords: ifn ggr; cd8 cells; expression; cd8 ... See more keywords
Borrelia‐primed and ‐infected mice deficient of interleukin‐17 develop arthritis after neutralization of gamma‐interferon
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DOI: 10.1093/femspd/ftx014
Abstract: &NA; The immune mechanisms responsible for development of Lyme arthritis are partially understood with interleukin‐17 (IL‐17) and gamma‐interferon (IFN‐&ggr;) playing a generally accepted role. Elevated levels of IL‐17 and/or IFN‐&ggr; have been reported in samples… read more here.
Keywords: arthritis; primed infected; mice; ifn ggr ... See more keywords
A purely quantitative form of partial recessive IFN‐&ggr;R2 deficiency caused by mutations of the initiation or second codon
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DOI: 10.1093/hmg/ddy275
Abstract: &NA; Mendelian susceptibility to mycobacterial disease (MSMD) is characterized by clinical disease caused by weakly virulent mycobacteria, such as environmental mycobacteria and Bacillus Calmette‐Guérin vaccines, in otherwise healthy individuals. All known genetic etiologies disrupt interferon… read more here.
Keywords: ifn ggr; partial recessive; ggr; ggr deficiency ... See more keywords
IFN‐&ggr; Influences Epithelial Antiviral Responses via Histone Methylation of the RIG‐I Promoter
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DOI: 10.1165/rcmb.2016-0392oc
Abstract: Abstract The asthmatic lung is prone to respiratory viral infections that exacerbate the symptoms of the underlying disease. Recent work has suggested that a deficient T‐helper cell type 1 response in early life may lead… read more here.
Keywords: ifn ggr; rig promoter; antiviral responses; ggr ... See more keywords
Vitamin D Counteracts an IL‐23‐Dependent IL‐17A+IFN‐&ggr;+ Response Driven by Urban Particulate Matter
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DOI: 10.1165/rcmb.2016-0409oc
Abstract: &NA; Urban particulate matter (UPM) air pollution and vitamin D deficiency are detrimentally associated with respiratory health. This is hypothesized to be due in part to regulation of IL‐17A, which UPM is reported to promote.… read more here.
Keywords: 17a ifn; urban particulate; ggr; vitamin ... See more keywords