Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep46580
Abstract: The mechanisms of immunoactivation by salt are now becoming clearer. However, those of immunosuppression remain unknown. Since clinical evidence indicates that salt protects proximal tubules from injury, we investigated mechanisms responsible for salt causing immunosuppression… read more here.
Keywords: jak1 stat1; salt; ifn inducible; stat1 ... See more keywords
Mouse B2 SINE elements function as IFN-inducible enhancers
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DOI: 10.7554/elife.82617
Abstract: Regulatory networks underlying innate immunity continually face selective pressures to adapt to new and evolving pathogens. Transposable elements (TEs) can affect immune gene expression as a source of inducible regulatory elements, but the significance of… read more here.
Keywords: inducible enhancers; ifn; ifn inducible; function ifn ... See more keywords