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   Articles with "ifn pathway" as a keyword



P11.10 The IFNγ pathway mediates brain metastasis formation of breast cancer

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recommendations! Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noz126.156

Abstract: In previous work we showed the prominence of the T-cell response in the formation of brain metastases of primary ER negative breast cancers (Mustafa et al, Acta Neuropathol 2018). We also showed that breast cancer… read more here.

Keywords: brain; ifn pathway; breast; breast cancer ... See more keywords

Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider

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recommendations! Published in 2023 at "RMD Open"

DOI: 10.1136/rmdopen-2022-002864

Abstract: Background Type I interferons (IFN-I) contribute to a broad range of rheumatic and musculoskeletal diseases (RMDs). Compelling evidence suggests that the measurement of IFN-I pathway activation may have clinical value. Although several IFN-I pathway assays… read more here.

Keywords: literature; pathway activation; activation; ifn pathway ... See more keywords

Granulin in renal tubular epithelia is associated with interstitial inflammation and activates the TLR9-IFN-α pathway in lupus nephritis

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recommendations! Published in 2024 at "Lupus"

DOI: 10.1177/09612033241232575

Abstract: Objective This study aimed to investigate the possible role of granulin (GRN) in activating the TLR9-IFN-α pathway in renal tubular epithelial cells (RTECs) and explore clues that RTECs regulate the micro-environment of inflammatory response in… read more here.

Keywords: grn; rtecs; ifn pathway; study ... See more keywords

The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum

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recommendations! Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.899998

Abstract: In leprosy patients, acute inflammatory episodes, known as erythema nodosum leprosum (ENL), are responsible for high morbidity and tissue damage that occur during the course of Mycobacterium leprae infection. In a previous study, we showed… read more here.

Keywords: nodosum leprosum; leprosy patients; blood; erythema nodosum ... See more keywords