Autoantibodies to cytoplasmic rods and rings in patients with hepatitis C virus infection treated with direct-acting antivirals: The role of prior treatment with interferon plus ribavirin.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterologia y hepatologia"
DOI: 10.1016/j.gastrohep.2018.08.005
Abstract: INTRODUCTION The cytoplasmic rods-rings (RR) pattern is found in hepatitis C (HCV) patients treated with interferon-ribavirin when studied with ANA-IIF. Ribavirin aggregates/induces antigenic changes in IMPDH-2, an enzyme necessary for ribavirin action. PATIENTS AND METHOD… read more here.
Keywords: rbv; treated direct; hcv; rods rings ... See more keywords
Real-world anti-viral treatment decisions among chronic hepatitis C patients in Taiwan: The INITIATE study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2018.10.020
Abstract: BACKGROUND/PURPOSE While direct-acting antiviral regimens have been approved for chronic hepatitis C (CHC) patients in Taiwan, reimbursement is limited to certain populations. Thus, pegylated interferon plus ribavirin (PEG-IFN/RBV) remains the standard of care for many… read more here.
Keywords: hepatitis; treatment; ifn rbv; peg ifn ... See more keywords
Before Direct-Acting Antivirals for Hepatitis C Virus: Evaluation of Core Protein R70Q and L/C91M Substitutions in Chronically Infected Brazilian Patients Unresponsive to IFN and/or RBV
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15010187
Abstract: Although chronic hepatitis C has been effectively treated with direct-acting antivirals (DAAs), the use of conventional therapy with peg-interferon (Peg-IFN) or (predominantly) ribavirin (RBV), remains widespread. R70Q/H and L/C91M amino acid substitutions in the hepatitis… read more here.
Keywords: c91m substitutions; ifn rbv; r70q c91m; rbv ... See more keywords