ZNF395 Is an Activator of a Subset of IFN-Stimulated Genes
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DOI: 10.1155/2017/1248201
Abstract: Activation of the interferon (IFN) pathway in response to infection with pathogens results in the induction of IFN-stimulated genes (ISGs) including proinflammatory cytokines, which mount the proper antiviral immune response. However, aberrant expression of these… read more here.
Keywords: znf395; response; ifn stimulated; activation ... See more keywords
IFN‐stimulated metabolite transporter ENT3 facilitates viral genome release
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DOI: 10.15252/embr.202255286
Abstract: An increasing amount of evidence emphasizes the role of metabolic reprogramming in immune cells to fight infections. However, little is known about the regulation of metabolite transporters that facilitate and support metabolic demands. In this… read more here.
Keywords: transporter ent3; transporter; metabolite transporter; ifn stimulated ... See more keywords
Fucosterol Isolated from Dietary Brown Alga Sargassum horneri Protects TNF-α/IFN-γ-Stimulated Human Dermal Fibroblasts Via Regulating Nrf2/HO-1 and NF-κB/MAPK Pathways
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DOI: 10.3390/antiox11081429
Abstract: Sargassum horneri is a well-known edible brown alga that is widely abundant in the sea near China, Korea, and Japan and has a wide range of bioactive compounds. Fucosterol (FST), which is a renowned secondary… read more here.
Keywords: tnf ifn; stimulated human; ifn stimulated; brown alga ... See more keywords
Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-α/IFN-γ- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20020117
Abstract: Recent studies have revealed that marine brown seaweeds contain numerous bioactive compounds which exhibit various bioactivities. The present study investigated the effect of low molecular weight fucoidan (SCF) isolated from Sargassum confusum, a brown alga,… read more here.
Keywords: inflammatory responses; tnf ifn; tnf; ifn stimulated ... See more keywords
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes
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DOI: 10.3390/v15041014
Abstract: Interferon-γ (IFN-γ) is a critical component of innate immune responses in humans to combat infection by many viruses, including human cytomegalovirus (HCMV). IFN-γ exerts its biological effects by inducing hundreds of IFN-stimulated genes (ISGs). In… read more here.
Keywords: effect; ifn stimulated; expression; ifn ... See more keywords
Twist1-IRF9 Interaction Is Necessary for IFN-Stimulated Gene Anti-Zika Viral Infection.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2300081
Abstract: An efficient immune defense against pathogens requires sufficient basal sensing mechanisms that can deliver prompt responses. Type I IFNs are protective against acute viral infections and respond to viral and bacterial infections, but their efficacy… read more here.
Keywords: ifn stimulated; twist1; infection; type ifns ... See more keywords