Surface antigen SAG1 mediates Toxoplasma gondii fitness and host cell attachment in IFNγ-stimulated cells
Sign Up to like & getrecommendations! Published in 2025 at "Infection and Immunity"
DOI: 10.1128/iai.00010-25
Abstract: ABSTRACT Toxoplasma gondii is an obligate intracellular protozoan parasite that can establish lifelong infections and cause severe disease in immunocompromised individuals. Interferon gamma (IFNγ) is a key host defense cytokine that induces a variety of… read more here.
Keywords: fitness; stimulated cells; host; sag1 ... See more keywords
ZNF395 Is an Activator of a Subset of IFN-Stimulated Genes
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/1248201
Abstract: Activation of the interferon (IFN) pathway in response to infection with pathogens results in the induction of IFN-stimulated genes (ISGs) including proinflammatory cytokines, which mount the proper antiviral immune response. However, aberrant expression of these… read more here.
Keywords: znf395; response; ifn stimulated; activation ... See more keywords
Unraveling the role of interferon-stimulated neutrophils: A promising biomarker for immunotherapy efficacy and prognosis in gastric adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.4_suppl.472
Abstract: 472 Background: Despite significant advancements in immunotherapy, the identification of effective predictive biomarkers for treatment response in gastric adenocarcinoma (GAC) remains a critical challenge. Discovering such biomarkers could enhance patient stratification and improve therapeutic outcomes.… read more here.
Keywords: stimulated neutrophils; immunotherapy efficacy; immunotherapy; gastric adenocarcinoma ... See more keywords
IFN‐stimulated metabolite transporter ENT3 facilitates viral genome release
Sign Up to like & getrecommendations! Published in 2023 at "EMBO Reports"
DOI: 10.15252/embr.202255286
Abstract: An increasing amount of evidence emphasizes the role of metabolic reprogramming in immune cells to fight infections. However, little is known about the regulation of metabolite transporters that facilitate and support metabolic demands. In this… read more here.
Keywords: transporter ent3; transporter; metabolite transporter; ifn stimulated ... See more keywords
Fucosterol Isolated from Dietary Brown Alga Sargassum horneri Protects TNF-α/IFN-γ-Stimulated Human Dermal Fibroblasts Via Regulating Nrf2/HO-1 and NF-κB/MAPK Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11081429
Abstract: Sargassum horneri is a well-known edible brown alga that is widely abundant in the sea near China, Korea, and Japan and has a wide range of bioactive compounds. Fucosterol (FST), which is a renowned secondary… read more here.
Keywords: tnf ifn; stimulated human; ifn stimulated; brown alga ... See more keywords
Fucoidan Isolated from Sargassum confusum Suppresses Inflammatory Responses and Oxidative Stress in TNF-α/IFN-γ- Stimulated HaCaT Keratinocytes by Activating Nrf2/HO-1 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20020117
Abstract: Recent studies have revealed that marine brown seaweeds contain numerous bioactive compounds which exhibit various bioactivities. The present study investigated the effect of low molecular weight fucoidan (SCF) isolated from Sargassum confusum, a brown alga,… read more here.
Keywords: inflammatory responses; tnf ifn; tnf; ifn stimulated ... See more keywords
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15041014
Abstract: Interferon-γ (IFN-γ) is a critical component of innate immune responses in humans to combat infection by many viruses, including human cytomegalovirus (HCMV). IFN-γ exerts its biological effects by inducing hundreds of IFN-stimulated genes (ISGs). In… read more here.
Keywords: effect; ifn stimulated; expression; ifn ... See more keywords
MMPP Attenuates the Inflammatory Response by Suppressing ROS and Proinflammatory Cytokine and Chemokine Production in TNF-α/IFN-γ-Stimulated Human Keratinocytes
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Microbiology and Biotechnology"
DOI: 10.4014/jmb.2508.08045
Abstract: Keratinocytes play a significant role in regulating skin immune homeostasis, and their dysregulation is central to chronic inflammatory disorders such as atopic dermatitis and psoriasis. Inflammatory mediators such as tumor necrosis factor alpha (TNF-α) and… read more here.
Keywords: tnf ifn; ifn stimulated; cytokine chemokine; ifn ... See more keywords
Twist1-IRF9 Interaction Is Necessary for IFN-Stimulated Gene Anti-Zika Viral Infection.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2300081
Abstract: An efficient immune defense against pathogens requires sufficient basal sensing mechanisms that can deliver prompt responses. Type I IFNs are protective against acute viral infections and respond to viral and bacterial infections, but their efficacy… read more here.
Keywords: ifn stimulated; twist1; infection; type ifns ... See more keywords
The Type 1 Diabetes-Associated Single Nucleotide Polymorphism rs1990760 in IFIH1 Is Associated with Increased Basal Type I IFNs and IFN-stimulated Gene Expression.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of immunology"
DOI: 10.4049/jimmunol.2400344
Abstract: Type 1 diabetes (T1D) is a chronic autoimmune disease that is caused by a combination of genetic and environmental risk factors. In this study, we sought to determine whether a known genetic risk factor, the… read more here.
Keywords: basal; type; type diabetes; expression ... See more keywords