Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
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DOI: 10.1136/rmdopen-2019-000989
Abstract: Objective In utero exposure of the fetus to Ro/La autoantibodies may lead to congenital heart block (CHB). In the mother, these autoantibodies are associated with activation of the type I interferon (IFN)-system. As maternal autoantibodies… read more here.
Keywords: ifn; ifn system; anti positive; activation ... See more keywords
Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.162404
Abstract: Hepatitis delta virus (HDV), a satellite virus of HBV, is regarded as the most severe type of hepatitis virus because of the substantial morbidity and mortality. The IFN system is the first line of defense… read more here.
Keywords: hdv infection; ifn; ifn system;