Characterization of interferon α and β receptor IFNAR1 and IFNAR2 expression and regulation in the uterine endometrium during the estrous cycle and pregnancy in pigs.
Sign Up to like & getrecommendations! Published in 2017 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2016.09.025
Abstract: Type I interferons (IFNs) bind to the heterodimeric receptor composed of IFN-α/β receptor 1 (IFNAR1) and IFN-α and β receptor 2 (IFNAR2) to transmit signals into the cell. It is well known that IFN-δ (IFND),… read more here.
Keywords: pregnancy pigs; uterine endometrium; pregnancy; ifnar1 ifnar2 ... See more keywords
Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of reproductive immunology"
DOI: 10.21203/rs.3.rs-1297654/v1
Abstract: Interferon-tau (IFNτ), as an antiluteolytic factor secreted by trophoderm during the pregnancy of ruminants, actually functions by activating the IFNτ receptor 1 (IFNAR1) and IFNτ receptor 2 (IFNAR2). However, it has not been clearly understood… read more here.
Keywords: ifnar2; bovine; ifn; ifnar1 ifnar2 ... See more keywords
Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.947169
Abstract: Type I interferons (IFNs) are potent inhibitors of viral replication. Here, we reformatted the natural murine and human type I interferon-α/β receptors IFNAR1 and IFNAR2 into fully synthetic biological switches. The transmembrane and intracellular domains… read more here.
Keywords: type; ifnar2; gfp mcherry; ifnar1 ifnar2 ... See more keywords