Abstract 674: CRISPR and drug screens identify ERK as the mediator of IFNg-induced melanoma growth inhibition
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DOI: 10.1158/1538-7445.am2023-674
Abstract: Interferon-gamma (IFNg) is critical for the success of immune checkpoint blockade therapy. Disruption of IFNg signaling makes tumors resistant to anti-PD-1/L1 treatment primarily by evasion of the growth inhibition (GI) induced by this cytokine. However,… read more here.
Keywords: growth inhibition; treatment; ifng induced; ifng ... See more keywords