HLA-B, HLA-C and KIR improve the predictive value of IFNL3 for Hepatitis C spontaneous clearance
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DOI: 10.1038/s41598-017-17531-7
Abstract: IFNL3 is the strongest predictor of spontaneous resolution (SR) of hepatitis C virus (HCV), however, consideration of IFNL3 genotype alone is of limited clinical value for the prediction of SR or chronic HCV infection. The… read more here.
Keywords: hla; hla hla; ifnl3; predictive value ... See more keywords
No association between IFNL3 (IL28B) genotype and response to peginterferon alfa-2a in HBeAg-positive or -negative chronic hepatitis B
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DOI: 10.1371/journal.pone.0199198
Abstract: Background & aims It has yet to be firmly established whether host IFNL3 (IL28B) genotype influences interferon responsiveness in patients with chronic hepatitis B. We investigated associations between single-nucleotide polymorphisms (SNPs) in the IFNL3 region… read more here.
Keywords: response; hepatitis; hbeag positive; genotype ... See more keywords