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Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01869-3
Abstract: Hemorrhagic cystitis (HC) is the major dose-limiting adverse effect of the clinical use ifosfamide (IFOS). The incidence of this side effect can be as high as 75%. Mesna has been used to reduce the risk…
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Keywords:
model;
ifosfamide;
damage;
hemorrhagic cystitis ... See more keywords
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Published in 2018 at "Neurophysiologie Clinique"
DOI: 10.1016/j.neucli.2018.06.032
Abstract: Introduction L’ifosfamide est un agent anticancereux alkylant utilise en oncologie pediatrique pour traiter de nombreux cancers de l’enfant. L’encephalopathie a l’Ifosfamide (EI) est un effet secondaire specifique survenant chez 3 a 19 % des patients. Cette neurotoxicite…
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Keywords:
apport eeg;
chez des;
ifosfamide;
dans diagnostic ... See more keywords
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Published in 2022 at "Drug Research"
DOI: 10.1055/a-1967-2066
Abstract: Abstract Mitochondrial dysfunction is a basic mechanism leading to drug nephrotoxicity. Replacement of defective mitochondria with freshly isolated mitochondria is potentially a comprehensive tool to inhibit cytotoxicity induced by ifosfamide on renal proximal tubular cells…
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Keywords:
renal proximal;
rptcs;
rat;
mitochondrial transplantation ... See more keywords
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Published in 2022 at "Journal of pediatric hematology/oncology"
DOI: 10.1097/mph.0000000000002473
Abstract: Ifosfamide is an important chemotherapeutic agent used in the therapeutic protocols of many malignant tumors. Central nervous system toxicity of ifosfamide manifests with encephalopathy in 10% to 30% of patients treated with ifosfamide. Thiamine and…
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Keywords:
thiamine;
encephalopathy rapid;
ifosfamide induced;
ifosfamide ... See more keywords
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Published in 2020 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155220963545
Abstract: Background Ifosfamide (IFO) is an alkylating agent used to treat broad range of malignancies. One of the life-threatening toxic effects is reversible neurotoxicity. In this report; we presented a case report of ifosfamide induced encephalopathy…
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Keywords:
induced encephalopathy;
ifosfamide induced;
child osteosarcoma;
ifosfamide ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1046199
Abstract: Osteosarcoma is one of the most prevalent primary bone malignancies in children and adolescents. Surgery and chemotherapy are the standard treatment methods of osteosarcoma. Methotrexate, adriamycin, and cisplatin, and methotrexate, adriamycin, cisplatin, and ifosfamide regimens…
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Keywords:
osteosarcoma;
limb salvage;
ifosfamide;
rate ... See more keywords