Articles with "ifosfamide" as a keyword



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α-Phellandrene attenuates tissular damage, oxidative stress, and TNF-α levels on acute model ifosfamide-induced hemorrhagic cystitis in mice

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Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"

DOI: 10.1007/s00210-020-01869-3

Abstract: Hemorrhagic cystitis (HC) is the major dose-limiting adverse effect of the clinical use ifosfamide (IFOS). The incidence of this side effect can be as high as 75%. Mesna has been used to reduce the risk… read more here.

Keywords: model; ifosfamide; damage; hemorrhagic cystitis ... See more keywords
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Apport de l’EEG dans le diagnostic de la neurotoxicité à l’Ifosfamide

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Published in 2018 at "Neurophysiologie Clinique"

DOI: 10.1016/j.neucli.2018.06.032

Abstract: Introduction L’ifosfamide est un agent anticancereux alkylant utilise en oncologie pediatrique pour traiter de nombreux cancers de l’enfant. L’encephalopathie a l’Ifosfamide (EI) est un effet secondaire specifique survenant chez 3 a 19 % des patients. Cette neurotoxicite… read more here.

Keywords: apport eeg; chez des; ifosfamide; dans diagnostic ... See more keywords
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Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells

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Published in 2022 at "Drug Research"

DOI: 10.1055/a-1967-2066

Abstract: Abstract Mitochondrial dysfunction is a basic mechanism leading to drug nephrotoxicity. Replacement of defective mitochondria with freshly isolated mitochondria is potentially a comprehensive tool to inhibit cytotoxicity induced by ifosfamide on renal proximal tubular cells… read more here.

Keywords: renal proximal; rptcs; rat; mitochondrial transplantation ... See more keywords
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Ifosfamide-induced Encephalopathy With Rapid Response to Thiamine: A Pediatric Case.

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Published in 2022 at "Journal of pediatric hematology/oncology"

DOI: 10.1097/mph.0000000000002473

Abstract: Ifosfamide is an important chemotherapeutic agent used in the therapeutic protocols of many malignant tumors. Central nervous system toxicity of ifosfamide manifests with encephalopathy in 10% to 30% of patients treated with ifosfamide. Thiamine and… read more here.

Keywords: thiamine; encephalopathy rapid; ifosfamide induced; ifosfamide ... See more keywords
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Ifosfamide induced encephalopathy in a child with osteosarcoma

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Published in 2020 at "Journal of Oncology Pharmacy Practice"

DOI: 10.1177/1078155220963545

Abstract: Background Ifosfamide (IFO) is an alkylating agent used to treat broad range of malignancies. One of the life-threatening toxic effects is reversible neurotoxicity. In this report; we presented a case report of ifosfamide induced encephalopathy… read more here.

Keywords: induced encephalopathy; ifosfamide induced; child osteosarcoma; ifosfamide ... See more keywords
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Mediating effect assessment of ifosfamide on limb salvage rate in osteosarcoma: A study from a single center in China

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1046199

Abstract: Osteosarcoma is one of the most prevalent primary bone malignancies in children and adolescents. Surgery and chemotherapy are the standard treatment methods of osteosarcoma. Methotrexate, adriamycin, and cisplatin, and methotrexate, adriamycin, cisplatin, and ifosfamide regimens… read more here.

Keywords: osteosarcoma; limb salvage; ifosfamide; rate ... See more keywords