β-Arrestin mediates the export of ciliary GPR161 but not Smoothened together with the BBSome and IFT machinery.
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DOI: 10.1242/jcs.263793
Abstract: Specific G protein-coupled receptors (GPCRs) exist on the ciliary membrane. Hedgehog signaling activation triggers the import of Smoothened into and export of GPR161 from cilia. The BBSome comprising eight Bardet-Biedl syndrome (BBS) proteins mediates GPCR… read more here.
Keywords: ift machinery; arrestin; gpr161; ift ... See more keywords