Serum levels of the IgA isotype switch factor TGF‐β1 are elevated in patients with COVID‐19
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DOI: 10.1002/1873-3468.14104
Abstract: We previously observed enhanced immunoglobulin A (IgA) responses in severe COVID‐19, which might confer damaging effects. Given the important role of IgA in immune and inflammatory responses, the aim of this study was to investigate… read more here.
Keywords: switch factor; isotype switch; covid; tgf ... See more keywords
Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching
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DOI: 10.3390/ijms231911132
Abstract: Patients with inflammatory bowel disease (IBD) produce enhanced immunoglobulin A (IgA) against the microbiota compared to healthy individuals, which has been correlated with disease severity. Since IgA complexes can potently activate myeloid cells via the… read more here.
Keywords: iga; myeloid cells; pathology; isotype switching ... See more keywords