1 H NMR‐based metabolomics study for identifying urinary biomarkers and perturbed metabolic pathways associated with severity of IgA nephropathy: a pilot study
Sign Up to like & getrecommendations! Published in 2017 at "Magnetic Resonance in Chemistry"
DOI: 10.1002/mrc.4573
Abstract: The severity of IgA nephropathy (IgAN), the most common primary glomerulonephritis, is judged on the basis of histologic and clinical features. A limited number of studies have considered molecular signature of IgAN for this issue,… read more here.
Keywords: severity iga; iga nephropathy; study; severity ... See more keywords
Complement activation in IgA nephropathy.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in immunopathology"
DOI: 10.1007/s00281-021-00882-9
Abstract: IgA nephropathy pathogenesis is incompletely understood, and this limits the development of disease-specific biomarkers and effective therapies. Evidence of complement activity in IgA nephropathy is well established. However, a growing body of research indicates complement… read more here.
Keywords: iga; complement activation; iga nephropathy; complement activity ... See more keywords
Juvenile dermatomyositis with IgA nephropathy: case-based review
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4229-4
Abstract: Juvenile dermatomyositis (JDM) is the most common childhood idiopathic inflammatory myopathy (IIM). It is characterized by the classic skin rash in the form of Gottron papules and heliotrope rash, and symmetric proximal muscle weakness. Renal… read more here.
Keywords: dermatomyositis; juvenile dermatomyositis; iga nephropathy; dermatomyositis iga ... See more keywords
The gut–kidney axis in IgA nephropathy: role of microbiota and diet on genetic predisposition
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3652-1
Abstract: Recent data suggest that gut-associated lymphoid tissue (GALT) plays a major role in the development of immunoglobulin A (IgA) nephropathy (IgAN). A genome-wide association study showed that most loci associated with the risk of IgAN… read more here.
Keywords: gut; iga nephropathy; gut kidney; role ... See more keywords
Lisinopril versus lisinopril and losartan for mild childhood IgA nephropathy: a randomized controlled trial (JSKDC01 study)
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Nephrology"
DOI: 10.1007/s00467-018-4099-8
Abstract: BackgroundPersistent proteinuria seems to be a risk factor for progression of renal disease. Its reduction by angiotensin-converting inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) is renoprotective. Our previous pilot study showed that 2-year lisinopril… read more here.
Keywords: childhood; mild iga; trial; iga nephropathy ... See more keywords
Clinical relevance of membrane attack complex deposition in children with IgA nephropathy and Henoch-Schönlein purpura
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Nephrology"
DOI: 10.1007/s00467-019-04445-x
Abstract: Background IgA nephropathy (IgAN) and Henoch-Schönlein purpura are common glomerular disorders in children sharing the same histopathologic pattern of IgA deposits within the mesangium, even if their physiopathology may be different. Repeated exposure to pathogens… read more here.
Keywords: henoch sch; iga nephropathy; deposition; nlein purpura ... See more keywords
IgA nephropathy: is a new approach beyond proteinuria necessary?
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Nephrology"
DOI: 10.1007/s00467-019-4202-9
Abstract: The amount of proteinuria continues to be one of the parameters that best correlates with the development of renal failure in any glomerular pathology. This circumstance is especially relevant when the analysis is limited to… read more here.
Keywords: nephrology; iga nephropathy; group group; remission ... See more keywords
Efficacy and safety of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for IgA nephropathy in children
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Nephrology"
DOI: 10.1007/s00467-021-05316-0
Abstract: IgA nephropathy (IgAN) is one of the most prevalent primary glomerulopathies in children. There are various studies investigating the efficacy of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) in adults with IgAN.… read more here.
Keywords: iga nephropathy; acei arb; angiotensin converting; converting enzyme ... See more keywords
Renal survival and risk factors in IgA nephropathy with crescents
Sign Up to like & getrecommendations! Published in 2020 at "International Urology and Nephrology"
DOI: 10.1007/s11255-020-02457-3
Abstract: Purpose The association between crescents and renal outcomes was inconsistent in a Chinese IgA nephropathy (IgAN) cohort, and limited research has investigated the prognosis of IgAN patients with crescents. Methods Between January 2008 and January… read more here.
Keywords: combined events; risk; iga nephropathy; patients crescents ... See more keywords
The role of body mass index on IgA nephropathy prognosis: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Urology and Nephrology"
DOI: 10.1007/s11255-022-03160-1
Abstract: Recent studies show that obese patients have worse outcomes in IgA nephropathy as compared to normal weight patients. We performed a systematic review and meta-analysis of prospective, retrospective, randomized and nonrandomized studies, which studied the… read more here.
Keywords: analysis; review meta; systematic review; iga nephropathy ... See more keywords
The influences of α-hemolytic Streptococcus on class switching and complement activation of human tonsillar cells in IgA nephropathy.
Sign Up to like & getrecommendations! Published in 2021 at "Immunologic research"
DOI: 10.1007/s12026-021-09223-2
Abstract: While β-hemolytic streptococcus (β-HS) infections are known to predispose patients to acute poststreptococcal glomerulonephritis, there is evidence that implicates α-hemolytic streptococcus (α-HS) in IgA nephropathy (IgAN). The alternative pathway of the complement system has also… read more here.
Keywords: iga nephropathy; activation human; hemolytic streptococcus; complement activation ... See more keywords