The NKT cell TCR repertoire can accommodate structural modifications to the lipid and orientation of the terminal carbohydrate of iGb3
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DOI: 10.1039/d2ra02373c
Abstract: Isoglobotrihexosylceramide (iGb3) is a known NKT cell agonist, however the specific interactions required to trigger NKT cell TCR activation in response to this mammalian glycolipid are not fully understood. Here we report the synthesis of… read more here.
Keywords: nkt cell; tcr repertoire; cell tcr; igb3 ... See more keywords