IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis
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DOI: 10.1007/s11033-020-05339-0
Abstract: Purpose We have previously identified insulin-like growth factor 2 (IGF2) and insulin-like growth factor 1 receptor (IGF1R) as essential proteins for tip cell maintenance and sprouting angiogenesis. In this study, we aim to identify other… read more here.
Keywords: igf binding; angiogenesis; binding proteins; absence serum ... See more keywords
What Happened to the IGF Binding Proteins?
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DOI: 10.1210/en.2017-00908
Abstract: Insulinlike growth factor (IGF) binding proteins (IGFBPs) 1 to 6 are high-affinity regulators of IGF activity. They generally inhibit IGF actions by preventing binding to the IGF-I receptor but can also enhance their actions under… read more here.
Keywords: igf binding; happened igf; binding proteins; growth ... See more keywords
Role of IGF-binding proteins in regulating IGF responses to changes in metabolism.
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DOI: 10.1530/jme-18-0016
Abstract: The IGF-binding protein family contains six members that share significant structural homology. Their principal function is to regulate the actions of IGF1 and IGF2. These proteins are present in plasma and extracellular fluids and regulate… read more here.
Keywords: igf binding; binding proteins; role igf; physiology ... See more keywords