IGF-1 and GLP-1 signaling: potential therapeutic target for neurological disorders – correspondence
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Medicine and Surgery"
DOI: 10.1097/ms9.0000000000000164
Abstract: Neuronal cell survival, proliferation, and neurogenesis are all dependent on insulin-like growth factor-1/glucagon like peptide-1 (IGF-1/GLP-1) signaling. In the last few decades, the downregulation of IGF-1 and GLP-1 has been linked to problems in the… read more here.
Keywords: glp; glp signaling; igf glp; neurological disorders ... See more keywords
Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27123878
Abstract: Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like symptoms. Our previous research suggests that mercury levels are directly associated with ALS progression.… read more here.
Keywords: rats exposed; igf glp; als like; glp signalling ... See more keywords