Trajectories of plasma IGF-1, IGFBP-3, and their ratio in the Mayo Clinic Study of Aging
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2018.02.015
Abstract: &NA; Insulin‐like growth factor 1 (IGF‐1) has been associated with osteoporosis, cardiovascular disease, cancer, neurodegenerative diseases, and mortality in middle and older aged adults. Cross‐sectionally, IGF‐1 decreases with age and levels of IGF‐1 are markedly… read more here.
Keywords: igfbp; age; clinic; igf igfbp ... See more keywords
Activation of IGF-1/IGFBP-3 signaling by berberine improves intestinal mucosal barrier of rats with acute endotoxemia.
Sign Up to like & getrecommendations! Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2017.11.012
Abstract: Insulin-like growth factor I (IGF-I) and binding protein 3 (IGFBP-3) play a role in the maintenance of gut mucosal barrier function. Nevertheless, IGF-I/IGFBP-3 and tight junction protein (TJP) expression in small intestinal mucosa are often… read more here.
Keywords: igfbp signaling; acute endotoxemia; igf; mucosal barrier ... See more keywords
Associations of GHR, IGF-1 and IGFBP-3 expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children
Sign Up to like & getrecommendations! Published in 2022 at "Adipocyte"
DOI: 10.1080/21623945.2022.2148886
Abstract: ABSTRACT Components of the growth hormone (GH) axis, such as insulin-like growth factor-1 (IGF-1), IGF-1 binding protein-3 (IGFBP-3), GH receptor (GHR) and GH-binding protein (GHBP), regulate growth and metabolic pathways. Here, we asked if serum… read more here.
Keywords: igf igfbp; expression; adipose tissue; obesity related ... See more keywords
Serum IGF-1, IGFBP-3 and their ratio: Potential biochemical growth maturity indicators
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Orthodontics"
DOI: 10.1186/s40510-017-0165-1
Abstract: BackgroundDetermination of skeletal maturation and remaining growth potential is an essential part of treatment planning in orthodontics. The aim of our study was to determine the relationship between IGF-1 levels, IGFBP-3 levels with CVM staging… read more here.
Keywords: igfbp; igf levels; stage; growth ... See more keywords
Insulin-like growth factor ternary complex components as biomarkers for the diagnosis of short stature.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of endocrinology"
DOI: 10.1530/eje-21-0475
Abstract: OBJECTIVE The diagnosis of growth hormone deficiency (GHD) in children is not always straightforward because IGF-1 or GH stimulation tests may not be able to discriminate GHD from constitutional delay of growth and puberty (CDGP)… read more here.
Keywords: ternary complex; short stature; ghd; growth ... See more keywords
Declining Levels and Bioavailability of IGF-I in Cardiovascular Aging Associate With QT Prolongation–Results From the 1946 British Birth Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.863988
Abstract: Background As people age, circulating levels of insulin-like growth factors (IGFs) and IGF binding protein 3 (IGFBP-3) decline. In rat cardiomyocytes, IGF-I has been shown to regulate sarcolemmal potassium channel activity and late sodium current… read more here.
Keywords: igf igfbp; prolongation; igfbp; qtc ... See more keywords
The impact of circulating IGF-1 and IGFBP-2 on cardiovascular prognosis in patients with acute coronary syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1126093
Abstract: Background While insulin-like growth factor 1 (IGF-1) exerts a cardioprotective effect in the setting of atherosclerosis, insulin-like growth factor binding protein 2 (IGFBP-2) is involved in metabolic syndrome. Although IGF-1 and IGFBP-2 are known to… read more here.
Keywords: igf igfbp; coronary syndrome; igfbp levels; acute coronary ... See more keywords
IGF-I and IGFBP-1 in Relation to Body Composition and Physical Performance in Female Olympic Athletes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.708421
Abstract: Introduction Insulin- like growth factor-I (IGF-I) is an anabolic hormone that may affect athletic performance in female athletes, and insulin-like growth factor binding protein-1 (IGFBP-1) is an important regulator of bioactive IGF-I. There is limited… read more here.
Keywords: female; body composition; igf igfbp; performance ... See more keywords
Correlation between Salivary Levels of IGF-1, IGFBP-3, IGF-1/IGFBP3 Ratio with Skeletal Maturity Using Hand-Wrist Radiographs
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19063723
Abstract: Objective: The relevance of growth determination in orthodontics is driving the search for the most precise and least invasive way of tracking the pubertal growth spurt. Our aim was to explore whether minimally invasive salivary… read more here.
Keywords: growth; igf igfbp; skeletal maturity;
Insulin-like Growth Factor 2 (IGF-2) and Insulin-like Growth Factor Binding Protein 7 (IGFBP-7) Are Upregulated after Atypical Antipsychotics in Spanish Schizophrenia Patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179591
Abstract: Insulin-like growth factor 2 (IGF-2) and IGF binding protein 7 (IGFBP-7) have been related to schizophrenia (SZ) due to their implication in neurodevelopment. The purpose of this study was to assess whether the alterations in… read more here.
Keywords: igf igfbp; like growth; growth factor; insulin like ... See more keywords
[Study on the consistency of IGF-1 and IGFBP-3 of peripheral whole blood and venous serum in children].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20220510-00462
Abstract: This study aimed to explore the consistency of insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) by detecting peripheral whole blood and venous serum among children. As a cross-sectional study, children who were… read more here.
Keywords: venous serum; igf igfbp; peripheral whole; whole blood ... See more keywords