Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells modelling SBMA.
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DOI: 10.1016/j.bpc.2017.05.003
Abstract: Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a motor neuron disease caused by the expansion of a polymorphic CAG tandem repeat encoding a polyglutamine (polyQ) tract in the androgen receptor… read more here.
Keywords: motoneuron derived; ionic currents; igf pacap; derived cells ... See more keywords