Insulin-like Growth Factor 1 Mediates Adrenal Development Dysfunction in Offspring Rats Induced by Prenatal Food Restriction.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2017.11.013
Abstract: BACKGROUND Our previous study demonstrated that prenatal food restriction (PFR) could induce the dysfunction of the hypothalamic-pituitary-adrenal axis and glucocorticoid-related glucose and lipid metabolic alterations in adult offspring rats. AIM OF THE STUDY To investigate… read more here.
Keywords: igf1 signaling; dysfunction; prenatal food; offspring rats ... See more keywords
Growth Hormone Signaling in Liver Diseases: Therapeutic Potentials and Controversies
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in Liver Disease"
DOI: 10.1055/a-2015-1359
Abstract: Growth hormone (GH) and downstream insulin-like growth factor 1 (IGF1) signaling mediate growth and metabolism. GH deficiency causes short stature or dwarfism, and excess GH causes acromegaly. Although the association of GH/IGF1 signaling with liver… read more here.
Keywords: liver; igf1 signaling; growth hormone; signaling liver ... See more keywords
Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00163-22
Abstract: Insulin and insulin-like growth factor 1 (IGF1) signaling is transduced by insulin receptor substrate 1 (IRS1) and IRS2. To elucidate physiological and redundant roles of insulin and IGF1 signaling in adult hearts, we generated mice… read more here.
Keywords: igf1 signaling; insulin igf1; factor; heart ... See more keywords