Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons
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DOI: 10.1016/j.neuroscience.2018.07.029
Abstract: Highlights • We have established a novel human astrocyte-neuron co-culture system.• Astrocytes provided contact-mediated support for neurite outgrowth.• IGF1R-impaired astrocytes are less able to protect neurons under stress conditions.• Microarray analysis of these astrocytes identified… read more here.
Keywords: loss igf1r; human astrocytes; astrocytes alters; igf1r ... See more keywords