IGF1R signalling is a guardian of self-tolerance restricting autoantibody production
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DOI: 10.3389/fimmu.2022.958206
Abstract: Objective Insulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these areas. IGF1R is broadly expressed by antigen-presenting cells (APC). Using mice immunised with… read more here.
Keywords: apcs; autoantibody production; production; igf1r signalling ... See more keywords