Transgenerational impairment of ovarian induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) associated with Igf2 and H19 in adult female rat.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology"
DOI: 10.1016/j.tox.2019.152311
Abstract: 2,3,7,8-Tetrachlorobenze-p-dioxin (TCDD), one of representive Endocrine Disrupting Chemicals (EDCs), has potential adverse effects on human health. Direct exposure to TCDD has been implicated in ovarian follicles development and functions deficits in adulthood. However, it is… read more here.
Keywords: tcdd; igf2 h19; dioxin tcdd; exposure ... See more keywords
Correlation between polymorphisms in IGF2/H19 gene locus and epithelial ovarian cancer risk in Chinese population.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.02.002
Abstract: To investigate the association between SNPs in human IGF2/H19 gene locus and epithelial ovarian cancer (EOC) risk, we performed a case-control study in 422 individuals (219 EOC patients and 203 cancer-free controls). Four SNPs (rs2525885,… read more here.
Keywords: risk; gene locus; eoc; igf2 h19 ... See more keywords
Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Oncology"
DOI: 10.3892/ijo.2022.5430
Abstract: Abnormalities of the insulin-like growth factor 2 (IGF2)-H19 locus with the overexpression of IGF2 are frequent findings in adrenocortical carcinoma (ACC). The present study assessed the expression of RNAs and microRNAs (miRNAs/miRs) from the IGF2-H19… read more here.
Keywords: acc; expression; igf2 h19; igf2 ... See more keywords