Autocrine IGF2 programmes β-cell plasticity under conditions of increased metabolic demand
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DOI: 10.1038/s41598-021-87292-x
Abstract: When exposed to nutrient excess and insulin resistance, pancreatic β-cells undergo adaptive changes in order to maintain glucose homeostasis. The role that growth control genes, highly expressed in early pancreas development, might exert in programming… read more here.
Keywords: igf2 programmes; autocrine igf2; cell plasticity; autocrine ... See more keywords