Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104372
Abstract: Recently, first insights into the regulation and the role of the RNA‐binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the… read more here.
Keywords: inflammatory; reader igf2bp2; igf2bp2 regulates; m6a reader ... See more keywords
IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
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DOI: 10.1038/s41418-019-0461-z
Abstract: The major function of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is to regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role in cancer, but the underlying mechanism is largely unknown.… read more here.
Keywords: regulates dancr; methyladenosine; igf2bp2 regulates; cancer ... See more keywords
IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation
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DOI: 10.3389/fmolb.2021.780089
Abstract: Insulin-like growth factor 2 (IGF2) mRNA-binding protein 2 (IGF2BP2) is an important posttranscriptional regulatory for stability and m6A modification. Here, we investigated the role of IGF2BP2 in non–small-cell lung cancer (NSCLC) proliferation. TCGA database was… read more here.
Keywords: regulates malat1; igf2bp2 regulates; nsclc proliferation; igf2bp2 ... See more keywords