Insulin‐like growth factor binding protein 4 inhibits proliferation of bone marrow mesenchymal stem cells and enhances growth of neurospheres derived from the stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3353
Abstract: Insulin‐like growth factor binding protein 4 (IGFBP‐4) was reported to trigger cellular senescence and reduce cell growth of bone marrow mesenchymal stem cells (BMSCs), but its contribution to neurogenic differentiation of BMSCs remains unknown. In… read more here.
Keywords: igfbp; stem cells; proliferation; growth ... See more keywords
CT‐IGFBP‐4 as a novel prognostic biomarker in acute heart failure
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12590
Abstract: Insulin‐like growth factor binding protein‐4 (IGFBP‐4) fragments have been shown to predict the risk of major adverse cardiovascular events, including segment‐elevation myocardial infarction, in patients with acute coronary syndrome. We evaluated the prognostic value of… read more here.
Keywords: failure igfbp; igfbp; acute heart; heart failure ... See more keywords
Trajectories of plasma IGF-1, IGFBP-3, and their ratio in the Mayo Clinic Study of Aging
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2018.02.015
Abstract: &NA; Insulin‐like growth factor 1 (IGF‐1) has been associated with osteoporosis, cardiovascular disease, cancer, neurodegenerative diseases, and mortality in middle and older aged adults. Cross‐sectionally, IGF‐1 decreases with age and levels of IGF‐1 are markedly… read more here.
Keywords: igfbp; age; clinic; igf igfbp ... See more keywords
Metabolic improvement after gastric bypass correlates with changes in IGF-regulatory proteins stanniocalcin-2 and IGFBP-4.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154886
Abstract: BACKGROUND Pregnancy-associated plasma protein-A (PAPP-A) is an enzyme that increases IGF-activity through cleavage of IGF-binding proteins (IGFBPs), primarily IGFBP-4, whereby bound IGF-I becomes released as a free molecule. The enzymatic activity of PAPP-A is irreversibly… read more here.
Keywords: igfbp; gastric bypass; papp; changes igf ... See more keywords
Levels of parathyroid hormone and IGF binding protein 1 and associations with mortality and hip fractures in older women
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-80527-7
Abstract: In this study we examined the effect of simultaneously elevated levels of parathyroid hormone (PTH) (≥ 65 ng/mL) and high levels of insulin-like growth factor-binding protein 1 (IGFBP-1) on the 10-year risk of all-cause mortality and… read more here.
Keywords: levels parathyroid; hip fractures; mortality; igfbp ... See more keywords
Diagnostic Value of IGFBP-2 in Predicting Preeclampsia before 20 Weeks of Pregnancy: A Prospective Nested Case-Control Study
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5075569
Abstract: Purpose To identify novel biomarker insulin-like growth factor binding protein-2 (IGFBP-2) associated with preeclampsia (PE) before 20 weeks of gestation and to explore the predictive value of plasma IGFBP-2 in PE. Methods A prospective nested… read more here.
Keywords: preeclampsia weeks; prospective nested; igfbp; value ... See more keywords
Abstract 1095: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) regulates mitochondrial dynamics, EMT and angiogenesis in progression of prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-1095
Abstract: Prostate cancer (PCa) is a major epithelial cancer among men and with the second highest incidence rate, worldwide. The high ratio of IGF-1/IGFBP-3 correlates with increased risk of many cancers including prostate cancer. In present… read more here.
Keywords: igfbp; prostate cancer; du145; cancer ... See more keywords
Abstract B006: The role of tumor specific IGFBP-3 in the onset and progression of skeletal muscle wasting in a murine model of pancreatic cancer
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.pancreatic24-b006
Abstract: Background: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer- related death and is highly associated with skeletal muscle wasting (SMW) that leads to treatment intolerance and reduced survival. Research substantiates the role… read more here.
Keywords: skeletal muscle; mice; cancer; igfbp ... See more keywords
Effects of gastric sleeve surgery on the serum levels of GH, IGF-1 and IGF-binding protein 2 in healthy obese patients
Sign Up to like & getrecommendations! Published in 2020 at "BMC Gastroenterology"
DOI: 10.1186/s12876-020-01309-9
Abstract: Background Bariatric surgery is an effective treatment for severe obesity. It also ameliorates diabetes independently of weight loss through mechanisms that are not fully understood. In this study, we investigated the levels of GH, IGF-1… read more here.
Keywords: igfbp; gastric sleeve; surgery; igf igf ... See more keywords
Serum IGF-1, IGFBP-3 and their ratio: Potential biochemical growth maturity indicators
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Orthodontics"
DOI: 10.1186/s40510-017-0165-1
Abstract: BackgroundDetermination of skeletal maturation and remaining growth potential is an essential part of treatment planning in orthodontics. The aim of our study was to determine the relationship between IGF-1 levels, IGFBP-3 levels with CVM staging… read more here.
Keywords: igfbp; igf levels; stage; growth ... See more keywords
Insulin-like growth factor-1 (IGF-1) levels in multiple sclerosis patients: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0297091
Abstract: Background and objective Multiple sclerosis (MS) is a chronic progressive autoimmune disorder of the central nervous system (CNS) that can cause inflammation, demyelination, and axon degeneration. Insulin-like growth factor-1 (IGF-1) is a single-chain polypeptide mainly… read more here.
Keywords: meta analysis; igfbp igfbp; blood levels; systematic review ... See more keywords