IGFBP3 inhibits angiotensin II-induced aortic smooth muscle cell phenotypic switch and MMPs expression.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental physiology"
DOI: 10.1113/ep088927
Abstract: NEW FINDINGS What is the central question of this study? Insulin like growth factor (IGF) 1 and its major binding protein IGFBP3 involves in collagen deregulation in several cardiovascular diseases. The role of IGFBP3 in… read more here.
Keywords: expression; igfbp3; smooth muscle; phenotypic switch ... See more keywords
Adipose-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicles Rescue Tendon Injury in Rat via the miR-19 a/IGFBP3 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells International"
DOI: 10.1155/2022/4197473
Abstract: Purpose Adipose-derived mesenchymal stem cells (ADSCs) are increasingly applied in tendon repair. However, the underlying mechanisms of ADSC-derived extracellular vesicles (EVs) in tendon healing are largely unknown. In this study, we investigated the effect of… read more here.
Keywords: igfbp3; proliferation; oxidative stress; adsc derived ... See more keywords
IGFBP3 Enhances Treatment Outcome and Predicts Favorable Prognosis in ABC-DLBCL
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oncology"
DOI: 10.1155/2023/1388041
Abstract: Chemoresistance is a key obstacle in the clinical treatment and management of activated B cell-like diffuse large B-cell lymphoma (ABC-DLBCL), which leads to the poor prognosis of patients. Exploring novel biomarkers to early warn drug… read more here.
Keywords: treatment; abc dlbcl; prognosis; igfbp3 ... See more keywords
Abstract 2371: Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor initiated oncogenesis through IGFBP3 mediated IGF1 induced Wnt activation
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2371
Abstract: Prostate cancer is the second most common cancer in men worldwide. The current treatment targeting androgen receptor (AR) expressing cells, androgen deprivation therapy (ADT), eventually fails in most prostate cancer patients who consequently develop castration… read more here.
Keywords: igfbp3; igf1; gli1 lineage; tumor ... See more keywords
Effects of insulin-like growth factor binding protein 3 on cell growth and tumorigenesis in oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/31772
Abstract: Background: This study was performed to investigate the effect of insulin-like growth factor binding protein 3 (IGFBP3) on the biological behavior of tumor cells and tumorigenesis of oral squamous cell carcinoma (OSCC). Methods: OSCC HB96,… read more here.
Keywords: protein; igfbp3; formation; cell growth ... See more keywords
IGF-1 and IGFBP3 as indirect markers of hepatic insulin resistance and their relation to metabolic syndrome parameters in liver steatosis patients
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine Regulations"
DOI: 10.2478/enr-2023-0009
Abstract: Abstract Objective. The aim of the present study was to assess insulin-like growth factor 1 (IGF-1) and IGF-binding protein 3 (IGFBP3) as markers of insulin resistance in patients with prediabetes and type 2 diabetes mellitus… read more here.
Keywords: igf igfbp3; insulin resistance; plasma levels; igfbp3 ... See more keywords
miR-196b/miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP3 expression in acute lymphoblastic leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology reports"
DOI: 10.3892/or.2016.5321
Abstract: MicroRNAs play critical roles in the progression of acute lymphoblastic leukemia (ALL). Previous studies have indicated that miR-196b and miR-1290 play critical roles in T-cell ALL (T-ALL) and B-cell ALL (B-ALL), respectively. Resveratrol, a natural… read more here.
Keywords: resveratrol; mir; igfbp3; 196b mir ... See more keywords
Downregulation of LOX promotes castration-resistant prostate cancer progression via IGFBP3
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer"
DOI: 10.7150/jca.61131
Abstract: The role of lysyl oxidase (LOX) in prostate cancer remains controversial. Studies have shown that LOX may inhibit the progression of prostate cancer (PCa), whereas other studies demonstrate that LOX may act as a tumor… read more here.
Keywords: cancer; igfbp3; lox; prostate cancer ... See more keywords