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   Articles with "igfbp7" as a keyword



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Insulin‐like growth factor binding protein 7 (IGFBP7), a link between heart failure and senescence

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recommendations! Published in 2022 at "ESC Heart Failure"

DOI: 10.1002/ehf2.14120

Abstract: Insulin like growth factor binding protein 7 (IGFBP7) is a marker of senescence secretome and a novel biomarker in patients with heart failure (HF). We evaluated the prognostic value of IGFBP7 in patients with heart… read more here.

Keywords: heart failure; insulin like; like growth; igfbp7 ... See more keywords

IGFBP7 contributes to epithelial‐mesenchymal transition of HPAEpiC cells in response to radiation

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28516

Abstract: Radiation‐induced lung injury (RILI) frequently occurs in patients with thoracic malignancies. In response to radiation, alveolar epithelial cells (AEC) undergo epithelial‐mesenchymal transition (EMT) and contribute to the pathogenesis of RILI. Insulin‐like growth factor binding protein… read more here.

Keywords: mesenchymal transition; response radiation; hpaepic cells; igfbp7 ... See more keywords
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Prognostic impact of tumor-specific insulin-like growth factor binding protein 7 (IGFBP7) levels in breast cancer: A prospective cohort study.

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recommendations! Published in 2021 at "Carcinogenesis"

DOI: 10.1093/carcin/bgab090

Abstract: The prognostic impact of insulin-like growth factor binding protein 7 (IGFBP7) in breast cancer is unclear. Host factors, including lifestyle, anthropometry, and metabolic profile, might influence tumor-specific IGFBP7. This study aimed to investigate whether IGFBP7… read more here.

Keywords: breast cancer; igfbp7; tumor specific; cancer ... See more keywords
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IGFBP7 enhances trophoblast invasion via IGF-1R/c-Jun signaling in unexplained recurrent spontaneous abortion.

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recommendations! Published in 2022 at "Reproduction"

DOI: 10.1530/rep-21-0501

Abstract: Insufficient trophoblast invasion at the maternal-fetal interface contributes to abortion-prone pregnancy. Cyclosporine A (CsA) can exert therapeutic effects on unexplained recurrent spontaneous abortion (URSA) by promoting trophoblast invasion. A previous study showed decreased expression of… read more here.

Keywords: abortion; trophoblast invasion; expression; igfbp7 ... See more keywords
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Mechanisms Underlying Increased TIMP2 and IGFBP7 Urinary Excretion in Experimental AKI.

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recommendations! Published in 2018 at "Journal of the American Society of Nephrology : JASN"

DOI: 10.1681/asn.2018030265

Abstract: BACKGROUND Recent clinical data support the utility/superiority of a new AKI biomarker ("NephroCheck"), the arithmetic product of urinary TIMP × IGFBP7 concentrations. However, the pathophysiologic basis for its utility remains ill defined. METHODS To clarify… read more here.

Keywords: timp2 igfbp7; igfbp7; aki; urinary timp2 ... See more keywords
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IGFBP7 and the Tumor Immune Landscape: A Novel Target for Immunotherapy in Bladder Cancer

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.898493

Abstract: Insulin-like growth factor binding protein-7 (IGFBP7) was recently reported to be a ligand of CD93, a potential target to normalize vasculature and attenuate immunotherapy. However, its role in the tumor microenvironment (TME) and immunotherapy response… read more here.

Keywords: immunotherapy; igfbp7; bladder cancer; tumor ... See more keywords
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Potential of Urine Biomarkers CHI3L1, NGAL, TIMP-2, IGFBP7, and Combinations as Complementary Diagnostic Tools for Acute Kidney Injury after Pediatric Cardiac Surgery: A Prospective Cohort Study

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recommendations! Published in 2023 at "Diagnostics"

DOI: 10.3390/diagnostics13061047

Abstract: Acute kidney injury (AKI) is common after pediatric cardiac surgery (CS). Several urine biomarkers have been validated to detect AKI earlier. The objective of this study was to evaluate urine CHI3L1, NGAL, TIMP-2, IGFBP7, and… read more here.

Keywords: aki; timp; chi3l1 ngal; igfbp7 ... See more keywords

Plasmodium-infected erythrocytes induce secretion of IGFBP7 to form type II rosettes and escape phagocytosis

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recommendations! Published in 2020 at "eLife"

DOI: 10.7554/elife.51546

Abstract: In malaria, rosetting is described as a phenomenon where an infected erythrocyte (IRBC) is attached to uninfected erythrocytes (URBC). In some studies, rosetting has been associated with malaria pathogenesis. Here, we have identified a new… read more here.

Keywords: type rosetting; infected erythrocytes; plasmodium infected; igfbp7 ... See more keywords