FcγR Binding and ADCC Activity of Human IgG Allotypes
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DOI: 10.3389/fimmu.2020.00740
Abstract: Antibody dependent cellular cytotoxicity (ADCC) is an Fc-dependent effector function of IgG important for anti-viral immunity and anti-tumor therapies. NK-cell mediated ADCC is mainly triggered by IgG-subclasses IgG1 and IgG3 through the IgG-Fc-receptor (FcγR) IIIa.… read more here.
Keywords: adcc activity; igg; igg allotypes; activity human ... See more keywords