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   Articles with "igg positive" as a keyword



Seizures and Encephalitis in Myelin Oligodendrocyte Glycoprotein IgG Disease vs Aquaporin 4 IgG Disease

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recommendations! Published in 2018 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2017.3196

Abstract: Importance Antibodies to myelin oligodendrocyte glycoprotein IgG (MOG-IgG) are increasingly detected in patients with non–multiple sclerosis–related demyelination, some of whom manifest a neuromyelitis optica (NMO) phenotype. Cortical involvement, encephalopathy, and seizures are rare in aquaporin… read more here.

Keywords: igg disease; mog igg; igg positive; disease ... See more keywords

Comparing the efficacy of efgartigimod and intravenous immunoglobulin on AQP4‐IgG‐positive neuromyelitis optica spectrum disorder during acute attacks

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recommendations! Published in 2025 at "British Journal of Clinical Pharmacology"

DOI: 10.1002/bcp.70190

Abstract: The aim of our study was to evaluate the efficacy of efgartigimod and intravenous immunoglobulin (IVIG) on AQP4‐IgG‐positive neuromyelitis optica spectrum disorder (NMOSD) patients during acute attacks. read more here.

Keywords: intravenous immunoglobulin; efgartigimod intravenous; positive neuromyelitis; igg positive ... See more keywords

Severe Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell Responses

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recommendations! Published in 2024 at "Journal of Clinical Immunology"

DOI: 10.1007/s10875-024-01718-5

Abstract: A patient with X-linked agammaglobulinemia (XLA) and severe tick-borne encephalitis (TBE) was treated with TBE virus (TBEV) IgG positive plasma. The patient’s clinical response, humoral and cellular immune responses were characterized pre- and post-infection. ELISA… read more here.

Keywords: tbe; positive plasma; igg positive; patient ... See more keywords
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Prolonged B-cell depletion after rituximab in AQP4-IgG-positive neuromyelitis optica spectrum disorder

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recommendations! Published in 2021 at "Journal of Neuroimmunology"

DOI: 10.1016/j.jneuroim.2021.577666

Abstract: Rituximab (a B-cell depleting monoclonal antibody) is increasingly utilized for treatment of different immune-mediated neurologic disorders, including aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder (AQP4-IgG-NMOSD). After an initial treatment course, the drug is generally reinfused when peripheral… read more here.

Keywords: rituximab; cell depletion; igg positive; cell ... See more keywords
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Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa

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recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-23267-w

Abstract: Although the COVID-19 pandemic has left no country untouched there has been limited research to understand clinical and immunological responses in African populations. Here we characterise patients hospitalised with suspected (PCR-negative/IgG-positive) or confirmed (PCR-positive) COVID-19,… read more here.

Keywords: pcr negative; igg positive; negative igg; clinical immunological ... See more keywords

Myelin Oligodendrocyte Glycoprotein Antibody (MOG-IgG)-Positive Optic Perineuritis

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recommendations! Published in 2020 at "Neuro-Ophthalmology"

DOI: 10.1080/01658107.2019.1607883

Abstract: ABSTRACT Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but the majority of cases are idiopathic. Myelin oligodendrocyte glycoprotein (MOG)-IgG-positive optic neuritis has been reported to be associated with optic nerve… read more here.

Keywords: myelin oligodendrocyte; optic perineuritis; mog igg; igg positive ... See more keywords
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Outcome prediction models in AQP4-IgG positive neuromyelitis optica spectrum disorders

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recommendations! Published in 2019 at "Brain"

DOI: 10.1093/brain/awz054

Abstract: Using an international data set of 441 patients with AQP4-IgG positive NMOSD, and a collective history of almost 2000 attacks, Palace et al. apply mathematical modelling to predict likelihood of relapse and disability at different… read more here.

Keywords: models aqp4; outcome prediction; igg positive; prediction models ... See more keywords

Rituximab as First‐Line Compared to Escalation Immunotherapy Is Associated With Lower Disability Accumulation in Aquaporin‐4‐IgG‐Positive Neuromyelitis Optica Spectrum Disorder: A Multicenter Cohort Study From Germany and the United Kingdom

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recommendations! Published in 2025 at "European Journal of Neurology"

DOI: 10.1111/ene.70243

Abstract: Aquaporin‐4‐IgG‐positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD) can cause significant disability after a single attack. Long‐term immunotherapy reduces disability accumulation, but the choice of first‐line therapy varies. In the United Kingdom, rituximab is typically used… read more here.

Keywords: first line; positive neuromyelitis; igg positive; aquaporin igg ... See more keywords

Retinal Nerve Fiber Layer May Be Better Preserved in MOG-IgG versus AQP4-IgG Optic Neuritis: A Cohort Study

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0170847

Abstract: Background Optic neuritis (ON) in patients with anti-myelin oligodendrocyte glycoprotein (MOG)-IgG antibodies has been associated with a better clinical outcome than anti-aquaporin 4 (AQP4)- IgG ON. Average retinal nerve fiber layer thickness (RNFL) correlates with… read more here.

Keywords: igg; average rnfl; mog igg; igg positive ... See more keywords

Orbital Ectopic Lymphoid Follicles with Germinal Centers in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorders

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recommendations! Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2017.01947

Abstract: Neuromyelitis optica spectrum disorders (NMOSDs) are important autoimmune central nervous system (CNS) astrocytopathy causing acute myelitis, optic neuritis (ON), and encephalitis associated with significant morbidities and mortality. It is important to diagnose NMOSDs early as… read more here.

Keywords: lymphoid follicles; ectopic lymphoid; igg positive; neuromyelitis optica ... See more keywords

An Abnormally High Neutrophil-to-Lymphocyte Ratio Is Not an Independent Outcome Predictor in AQP4-IgG-Positive NMOSD

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recommendations! Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.628024

Abstract: Background The neutrophil-to-lymphocyte ratio (NLR) has been investigated in many autoimmune conditions as a biomarker of inflammation and/or disease activity. The role of NLR in AQP4-IgG-positive neuromyelitis optica spectrum disorders (NMOSD) is far from clear.… read more here.

Keywords: positive nmosd; igg positive; neutrophil lymphocyte; lymphocyte ratio ... See more keywords