ST6Gal1 in plasma is dispensable for IgG sialylation.
Sign Up to like & getrecommendations! Published in 2022 at "Glycobiology"
DOI: 10.1093/glycob/cwac039
Abstract: The glycosylation of IgG has attracted increased attention due to the impact of N-glycan modifications at N297 on IgG function, acting primarily through modulation of Fc domain conformation and Fcγ receptor binding affinities and signaling.… read more here.
Keywords: igg sialylation; sialylation; st6gal1 plasma; st6gal1 ... See more keywords
Response to Oswald et al.: ST6Gal1 in plasma is dispensable for IgG sialylation.
Sign Up to like & getrecommendations! Published in 2022 at "Glycobiology"
DOI: 10.1093/glycob/cwac055
Abstract: The presence or absence of terminal sialic acid residues in the sugar moiety attached to the Fc-domain of IgG molecules modulates IgG activity and is associated with autoimmune or infection related inflammation. In a recent… read more here.
Keywords: st6gal1 plasma; sialylation; igg sialylation; response oswald ... See more keywords
Bazedoxifene does not share estrogens effects on IgG sialylation
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285755
Abstract: The incidence of rheumatoid arthritis (RA) increases at the same time as menopause when estrogen level decreases. Estrogen treatment is known to reduce the IgG pathogenicity by increasing the sialylation grade on the terminal glycan… read more here.
Keywords: igg sialylation; sialylation; estrogen treatment; bazedoxifene ... See more keywords