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Published in 2020 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2020.100789
Abstract: Purpose Immunoglobulin G4-related disease is a systemic fibroinflammatory disease of unknown etiology. Immunoglobulin G4-related ophthalmic disease (IgG4-ROD) can manifest in multiple ways, but lacrimal sac involvement is rare. We present the first case in Chinese…
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Keywords:
immunoglobulin related;
igg4 rod;
lacrimal sac;
case ... See more keywords
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Published in 2021 at "Diagnostic and interventional imaging"
DOI: 10.1016/j.diii.2021.06.006
Abstract: PURPOSE The purpose of this prospective study was to determine the capabilities of intravoxel incoherent motion (IVIM) MRI at 3 Tesla in discriminating between IgG4-related orbital disease (IgG4-ROD) and other causes of orbital inflammation. MATERIALS…
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Keywords:
igg4;
igg4 rod;
orbital inflammation;
causes orbital ... See more keywords
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Published in 2021 at "Orbit"
DOI: 10.1080/01676830.2021.1962365
Abstract: PURPOSE To analyse the incidence and characteristics of ocular adnexal mucosa-associated lymphoid tissue lymphoma (OAML) with immunoglobulin G4 (IgG4)-related ophthalmic disease (IgG4-ROD), and to compare with IgG4-negative OAML. METHODS We enrolled 130 patients with pathology-confirmed…
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Keywords:
igg4;
igg4 rod;
disease;
igg4 positive ... See more keywords
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Published in 2019 at "Current Eye Research"
DOI: 10.1080/02713683.2019.1627462
Abstract: ABSTRACT Purpose: To determine the prevalence, clinical manifestations, and treatment outcomes of IgG4-related ophthalmic disease (IgG4-ROD) in previously diagnosed idiopathic orbital inflammation (IOI). Materials and Methods: Thirty one surgically treated patients with IOI between 1990…
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Keywords:
ophthalmic disease;
igg4;
igg4 rod;
related ophthalmic ... See more keywords
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Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/5651506
Abstract: IgG4-related disease (IgG4-RD) affects multiple organs and is characterized by immune-mediated inflammation and fibrosis; IgG-RD affecting orbital tissue is known as IgG4-related ophthalmic disease (IgG4-ROD). This research is aimed at exploring whether symptom duration and…
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Keywords:
igg4 related;
disease;
igg4 rod;
relapse ... See more keywords
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Published in 2023 at "Stem Cells International"
DOI: 10.1155/2023/2742839
Abstract: Objective This study is aimed at discussing the value of RNA interference technology on inhibiting lacrimal gland fibrosis in IgG4-related ocular disease (IgG4-ROD). Methods Six patients with IgG4-ROD who came to the hospital for surgical…
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Keywords:
igg4 rod;
lacrimal gland;
apoptosis;
proliferation ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052556
Abstract: The purpose of this present study was to investigate the distribution and expression of chymase in the lacrimal glands (LGs) of patients afflicted with IgG4-related ophthalmic disease (IgG4-ROD). LGs from patients with severe canalicular obstruction…
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Keywords:
chymase lacrimal;
igg4 rod;
lgs;
chymase ... See more keywords
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Published in 2022 at "Life"
DOI: 10.3390/life12101660
Abstract: Non-specific orbital inflammation (NSOI) and IgG4-related orbital disease (IgG4-ROD) are currently treated with non-specific immunosuppressive agents based on non-randomized, uncontrolled studies. Therefore, relapses and prolongated courses are common and remain challenging. For a more specific…
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Keywords:
lymphoma;
igg4 rod;
pathophysiology;
progression orbital ... See more keywords
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Published in 2017 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2017.7780
Abstract: Immonoglobulin G4-related ophthalmic disease (IgG4-ROD) is a IgG4-RD and exhibits two main characteristics: Fibrosis that is not necessarily marked histopathologically; and frequent formation of germinal centers (GCs). Follicular B helper T (Tfh) cells are now…
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Keywords:
patients igg4;
tfh;
igg4 rod;
tfh cells ... See more keywords