Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity and self-interactions: Experimental assessment and computational predictions of domain interactions
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DOI: 10.1080/19420862.2021.1991256
Abstract: ABSTRACT Human/humanized IgG4 antibodies have reduced effector function relative to IgG1 antibodies, which is desirable for certain therapeutic purposes. However, the developability and biophysical properties for IgG4 antibodies are not well understood. This work focuses… read more here.
Keywords: chain; viscosity; igg1; heavy chain ... See more keywords